Project Grant R01NS142764
- Federal Project Grant Award Summary Strokebridge Inc. received a $1,070,714 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, awarded August 6, 2025, with completion targeted for June 30, 2030. This research project aims to identify the specific cortical motor areas and brainstem motor pathways that contribute to preserved hand flexion function and...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded Massachusetts General Hospital $470,786 under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program on May 15, 2025, with completion targeted for March 31, 2030. This Project Grant supports investigator-initiated research examining the mechanisms linking aging, immune dysfunction, and vascular contributions to cognitive impairment and dementia...
- Federal Grant Award Summary Brigham & Women's Hospital Inc. received a $3.69M Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) effective September 15, 2025, through September 14, 2029. The award funds development of specialized Large Language Models (LLMs) designed to optimize comparative effectiveness research (CER) in Alzheimer's disease and related dementias (ADRD). The project addresses a critical gap in real-world evidence by extracting...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded Stanford University a $125,685 Project Grant on August 9, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to develop a bioactive material intervention for post-stroke dementia. The research will culminate in the development of an injectable hydrogel embedded with urokinase plasminogen activator (UPA) and plasmid DNA encoding...
- Federal Project Grant Award Summary Brigham and Women's Hospital Inc. received a $549,256 Project Grant awarded on June 6, 2025, by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award supports a five-year research project with a completion date of May 31, 2030, investigating the regulation of astrocyte responses in central nervous system (CNS) inflammation, with...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke awarded the University of Michigan a $233,280 Project Grant (CFDA 93.853, Extramural Research Programs in the Neurosciences and Neurological Disorders) effective March 1, 2026 through February 28, 2031. The award supports research to identify modifiable systems factors and telestroke-specific determinants associated with delays in acute ischemic stroke (AIS) treatment delivery. Specifically, the research will...
- Federal Grant Award Summary The University of Pennsylvania received a $644,345 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective February 11, 2026, with a completion date of December 31, 2030. The project deliverable is a multicenter randomized controlled trial evaluating MyStroke, a web-based, personalized video-based stroke...
- Federal Project Grant Award Summary Brigham & Women's Hospital Inc. received a $864,552 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective August 1, 2025 through July 31, 2027. The award funds research to optimize novel drug compounds for the treatment of essential tremor (ET), a chronic progressive neurological disease affecting...
- Federal Grant Award Summary Brigham & Women's Hospital Inc. received a $420,251 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, effective May 6, 2025, with a completion date of March 31, 2030. The award supports research on encapsulated cell-based oncolytic virus therapy for glioblastoma (GBM), the most lethal primary brain tumor. The...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded the University of Wisconsin–Madison a Project Grant totaling $494,240 under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, effective February 16, 2026, through January 31, 2031. This award funds a five-year research investigation into microRNA (miRNA) degradation mechanisms in post-stroke brain tissue, specifically examining...
Brigham & Women's Hospital Inc. received a $716,816 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective March 17, 2026, with completion targeted for January 31, 2031. The award supports SOCIALBIT2, a research initiative that deploys an artificial intelligence (AI) algorithm—operationalized on smartwatch devices—to objectively measure social connection in stroke survivors. The system utilizes ambient audio features to detect minutes of social interaction without recording raw audio data, addressing a critical measurement gap in stroke recovery research where traditional self-report surveys are limited by patient cognitive and language deficits. The project involves a three-month observational study of approximately 200 ischemic stroke patients who will wear SOCIALBIT-equipped smartwatches in their natural, everyday environments following hospitalization. The technology provides continuous, high-resolution tracking of social interaction time to inform intervention timing and strategies for this at-risk population. This represents the first objective assessment of social connection in stroke survivors conducted outside controlled hospital settings, advancing both measurement science and evidence-based intervention design for post-stroke recovery outcomes.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $716.8k | 3/19/26 |