Project Grant R01NS142167
Award Date
4/15/25
Completion Date
3/31/30
Dollars Obligated
$500K
Federal Agency
National Institute of Neurological Disorders and Stroke
Federal Grant Program
93.853
Assistance Type
Project Grant
Place of Performance
La Jolla, CA 92037, USA
Similar Awards
This $249,535 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) supports research to elucidate the role of astrocytes in reorganizing glutamate receptor expression and facilitating long-term potentiation (LTP) in spinal nociceptive circuits after neonatal injury. The research aims to advance understanding of how neuron-glial interactions contribute to persistent changes in synaptic plasticity underlying the priming of pain pathways following...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $441,500 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Duquesne University of the Holy Spirit. The purpose of this 3-year grant, beginning September 2023, is to utilize laboratory data and computational 3-D modeling to analyze the role of the central amygdala in neuropathic pain. Specifically, the project aims to build a proof-of-concept 3-D...
This $560,934 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports innovative research focused on understanding the neural coding and control of pain detection in the somatosensory cortex. The key objectives are to: 1) Define the temporal patterns and characterize the local field potential (LFP) properties of the primary somatosensory...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $764,659.00 to the University of Cincinnati to investigate the role of neurovascular interactions in neuropathic spontaneous pain. The research aims to characterize how local vascular movement triggers neuropathic spontaneous pain, determine how mechanoreceptors in sensory...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under CFDA 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders provides $158,512 to the University of Pittsburgh to conduct research aimed at understanding the role of orexinergic neurons in the spinal cord and their contribution to chronic pain. The research will use physiological and behavioral approaches, including two-photon calcium imaging and chemogenetic...
This federal Project Grant award of $738,566, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to investigate the circuit mechanisms that regulate somatosensory feedback in the brain. The research aims to determine if similar inhibitory mechanisms exist across the body and somatosensory modalities to dynamically adjust sensory transmission...
This Project Grant award, funded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to expose undergraduate students to pain and neuroscience research with a focus on pain inequities. The $129,113 award supports the Summer Program to Advance Research and Equity in Pain and Neurological Health (SPARQ), a 9-week mentored research and skills building program for...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will fund research to define the contribution of Macrophage Migration Inhibitory Factor (MIF) and its downstream signaling to spinal cord injury (SCI)-induced neuropathic pain. The $341,958 award, effective March 15, 2025 through February 28, 2030, will support a multidisciplinary,...
This $124,713 project grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to identify the neural circuit basis for neuropathic pain in the parabrachial nucleus (PBN) region of the brain. The primary goals are to: (1) understand how different pain-related stimuli are integrated in the PBN, (2) determine if specific PBN neuron subtypes...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will fund research to investigate sex differences in the neural circuitry underlying chronic pain susceptibility. The $191,189 award to the University of Maryland, Baltimore aims to clarify how the sex-dependent effects of the neuropeptide CGRP on the bed nucleus of the stria terminalis...