Project Grant R01NS141928
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded Kenyon College a Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The $454,424 grant, effective April 1, 2025 through March 31, 2028, aims to characterize the cellular and molecular mechanisms of Schwann cell demyelination and identify factors that promote peripheral remyelination using a novel larval zebrafish model. The project will test...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $377,262 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The University of Kentucky Research Foundation. The grant, awarded on August 15, 2025, supports research to investigate the mechanism underlying sphingoid base-induced neurotoxicity in neurodegenerative diseases. Specifically, the project will use a transgenic mouse model to dissect the...
- This federal Project Grant award for $102,876.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The funding supports research by Temple University-Of The Commonwealth System Of Higher Education to investigate the role of protein palmitoylation in axon degeneration, a key mechanism underlying diverse neurological conditions. The research aims to better...
- This federal Project Grant award of $451,822 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research by Oregon Health & Science University to study the distinct molecular profiles and functions of "pioneer" and "follower" neurons during nervous system development. The project aims to determine the specific transcriptional profiles that...
- This Project Grant award of $426,313, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), supports research at The Johns Hopkins University to investigate the signaling pathways that disrupt neurofilament (NF) phosphorylation dynamics and lead to NF hyperphosphorylation, a pathology associated with neurodegenerative diseases such as amyotrophic lateral...
- This federal Project Grant award, valued at $147,486, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The purpose of this award is to investigate the function of a ciliary protein in neural development, with a focus on uncovering novel molecular mechanisms involved in synapse formation that may be relevant to neurological disorders. Using C. elegans as...
- This $1,002,148 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research on the role of autophagy, a cellular process for clearing damaged organelles and inclusions, in neurodegeneration. The research aims to determine how levels of the lipid phosphatidylinositol 3-phosphate (PI(3)P) regulate autophagy in neurons, including...
- This $536,617 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) will support research conducted by Oregon Health & Science University (OHSU) to understand the mechanisms of adult neural regeneration using planarian and zebrafish model organisms. The research aims to elucidate how adult stem cells can generate the appropriate diversity of...
- This Project Grant award of $100,272.00 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to understand how axon guidance is regulated in the mature nervous system. The research aims to identify molecular and cellular mechanisms that regulate axon regeneration and guidance, with a focus on using the Caenorhabditis elegans model system to study an...
- This Project Grant award, valued at $232,524, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award will support research at Stony Brook University to investigate the role of the AMPK signaling pathway in regulating energy production and usage during the myelination process in oligodendroglial cells. The goal is to better understand...
This $441,195 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to define molecular pathways that drive neurodegeneration and identify ways to block axon and synapse loss in patients. The project aims to build on prior work identifying the SARM1 protein as a key regulator of axon degeneration, and to explore the role of the DWNK kinase in this process. The award, with a performance period from August 1, 2025 to April 30, 2030, is funding research conducted by Oregon Health & Science University to advance the understanding of neural circuit dysfunction caused by nervous system injury and neurodegenerative diseases.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $441.2k | 7/25/25 |