This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support research to understand the molecular mechanisms regulating axon regeneration after spinal cord injury. The $1,006,322 award to the University of California, San Diego will fund experiments using a novel patch-based single-cell RNA sequencing approach to refine a regeneration classifier, investigate the roles of mitochondrial biogenesis and antioxidant response, and analyze age-related changes in axon regeneration. This research aims to provide a greater understanding of neuron-intrinsic control of axon regeneration, laying the groundwork for developing therapeutic interventions to promote repair and recovery after spinal cord injury.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $18.0k | 2/25/25 | ||
| Not listed | $494.2k | 7/8/24 | ||
| Not listed | $494.2k | 7/8/24 |