This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), provides $582,246 to the University of Rochester to study stem cell-based therapies for neurological and neurodegenerative disorders. The key focus is developing cutting-edge in vivo imaging and neurophysiology methods to track the structural and functional dynamics of human...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, provides $2,307,075 to The Leland Stanford Junior University to conduct innovative research aimed at defining mechanisms of neurodegenerative diseases and developing therapeutic strategies. The key research efforts include: using yeast and human genetics to identify novel...
This $1,341,874 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program supports research focused on understanding the molecular mechanisms that control dendrite development, mechano-sensation exhibited by Drosophila dendritic arborization (DA) neurons, and mechanisms underlying dendrite and axon regeneration after injury. The primary...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $385,500.00 to The Leland Stanford Junior University to develop an inducible and multiplexed CRISPR-based gene regulation system to study neuronal activity and regeneration. The key products and services to be delivered include: 1) Engineering an inducible system capable of...
The Trustees of Columbia University in the City of New York (Columbia University), through its Health Sciences Division, was awarded a $445,009 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The grant's objective is to develop approaches for introducing developmentally-relevant inputs and reading out neuronal activity in human brain organoids to...
This $1,006,322 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) will fund research to develop a regeneration classifier that can predict the regenerative potential of diverse neuronal types after spinal cord injury. The research, conducted by the University of California, San Diego, will expand on the team's prior success in using patch-based...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $469,898.00 to Yale University to conduct research on mechanisms that support raphespinal tract plasticity and regeneration after spinal cord injury. The project aims to use anatomy, spatial transcriptomics, and intersectional in vivo chemogenetics to define the capacity...
This federal Project Grant award of $769,352.00 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program will support the development of an engineered bioprinting platform to study neural migration in brain assembloids - complex 3D models that combine distinct brain organoids to better capture regional interactions critical for neurodevelopment. The award will enable researchers at The Leland Stanford Junior University to: 1) Evaluate...
The $258,342 Project Grant from the National Institutes of Health's National Institute of Neurological Disorders and Stroke will support research into the mechanisms of dendritic tiling at Stanford University. Specifically, the grant will fund two specific aims: first, to test the hypothesis that activity-dependent mechanisms result in tiling of dendrites in C. elegans using live imaging of neighboring neurons labeled with distinct fluorescent reporters; and second, to assess the impact of...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $1,282,359.00 to support research on the regulation of generation and functions of intermediate progenitors in neural stem cell lineages. The 5-year project, starting on July 1, 2024 and running through May 31, 2029, will be conducted by the Regents of the University of Michigan....