Project Grant R01NS134596
Award Date
7/15/24
Completion Date
6/30/29
Dollars Obligated
$632K
Federal Agency
National Institute of Neurological Disorders and Stroke
Federal Grant Program
93.853
Assistance Type
Project Grant
Place of Performance
Houston, TX 77030, USA
Similar Awards
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $478,732 to Seattle Children's Hospital to characterize the cellular and molecular features of human cerebellar progenitor zones. The research leverages expertise in human cerebellar development and access to fetal tissue to conduct in vitro assays, live imaging, and...
The National Institute of Neurological Disorders and Stroke (NINDS), part of the Department of Health and Human Services, awarded a $4,528,840 Project Grant to The Salk Institute For Biological Studies under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The three-year award beginning August 19, 2022 will fund research to functionally dissect cerebellar output circuits that orchestrate limb motor control. Specifically, the grantee will...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $503,439 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the University of Colorado-Denver to conduct research on the functional roles of inhibitory cerebellar outputs. This 4-year project aims to advance the understanding of how the cerebellum, a critical region for motor control, tunes its own teaching signals and actuates motor control through...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $242,310 to Baylor College of Medicine to study the effects of the NR2E1 mutation on cellular and molecular determinants of neurogenesis. The research aims to understand how a specific NR2E1 mutation (I385T) affects the function of this transcription factor, which is...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $605,523 Project Grant (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders) to The Trustees of Columbia University in the City of New York to support research aimed at developing therapies to restore circuit function in cerebellar degeneration. The research will study a mouse model of cerebellar degeneration to determine how the loss of Purkinje cell synapses contributes to...
This federal Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) provides $296,920 to Baylor College of Medicine to study the neuronal mechanisms of CASK-related disorders, which are characterized by intellectual disability and epilepsy. The goal is to determine how the loss of the CASK protein in inhibitory neurons alters synaptic function and contributes to the development of these...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $676,388 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to St. Jude Children's Research Hospital Inc. The funding supports research to investigate how proteins involved in controlling neuronal migration and polarity, such as PARD6A and SIAH2, are linked to changes in chromatin organization during neuronal development. The goal is to provide a better...
This federal Project Grant award, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to investigate the role of neuronal primary cilia in regulating the excitation-inhibition balance within the mature brain's neural circuits. The $290,688 award to Brandeis University will fund a 1-year research project to determine the source of somatostatin...
This National Institute of Neurological Disorders and Stroke (NINDS) Project Grant award under CFDA 93.853, Extramural Research Programs in the Neurosciences and Neurological Disorders, provides $190,485 to the Trustees of Indiana University (Indiana University Indianapolis) to investigate the molecular mechanisms underlying differentiation failure in neuroepithelial stem cells with NF2 gene mutations. The primary objectives are to: (1) identify the cellular hierarchy in NF2-deficient stem cells...
This $1,008,977 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to understand the development and evolution of the human cerebral cortex. The key objectives are to study human-specific neural progenitor cell types in the outer subventricular zone, which play a critical role in the expansion of the human brain, and explore...