Project Grant R01MH138528
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a $762,566 Project Grant to the University of Maryland, Baltimore effective April 1, 2026, through December 31, 2030, under the Mental Health Research Grants program (CFDA 93.242). The award funds comprehensive multi-omic and synaptic imaging research to quantify cerebellar mechanisms underlying Autism Spectrum Disorders (ASDs). The research will generate single-nuclei multi-omic profiles analyzing gene expression...
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded Washington University a Project Grant of $811,412 under the Mental Health Research Grants program (CFDA 93.242) on May 1, 2026, with a completion date of February 28, 2031. This grant funds research to establish the specificity and scalability of motor imitation assessments as a biomarker for Autism Spectrum Disorder (ASD). The project combines innovative wearable high-density diffuse optical tomography...
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded Children's Research Institute a Project Grant of $654,005 under CFDA 93.242 (Mental Health Research Grants) on June 1, 2026, with a completion date of March 31, 2031. This award funds basic neuroscience research investigating the function of the paralaminar nucleus of the amygdala (PL) from adolescence to early adulthood using mouse models. The research seeks to advance understanding of how late-maturing...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded Washington University a Project Grant totaling $450,797 under the Mental Health Research Grants program (CFDA 93.242) to advance autism spectrum disorder (ASD) diagnosis and understanding through motor imitation biomarker research. The award, obligated on June 3, 2026, with a completion date of June 2, 2028, supports research to establish motor imitation deficits as a specific, objective biomarker for ASD that can...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a $534,191 Project Grant to The Trustees of Columbia University in the City of New York (Health Sciences Division) on April 1, 2026, through the Mental Health Research Grants program (CFDA 93.242). The award supports research through December 31, 2030, focusing on the development of robust fine-mapping tools and novel statistical methods for genetic discovery in neuropsychiatric traits using deep phenotype data....
- Federal Project Grant Award Summary Emory University received a $156,500 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) effective September 1, 2025, through August 31, 2027. The research project, "Investigating the Neuronal Function of ZNF185," delivers scientific investigation into the role of zinc-finger protein 185 (ZNF185) in synaptic function and neural development. The research employs a recently...
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded Washington University a $735,920 Project Grant effective June 1, 2026, through February 28, 2031, under the Mental Health Research Grants program (CFDA 93.242) to investigate neural mechanisms underlying threat learning and avoidance behaviors. The research focuses on characterizing a newly identified neuron population in the supramammillary nucleus (SUM) that responds to diverse stressors and plays...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded University of Colorado-Denver $429,000 under the Mental Health Research Grants program (CFDA 93.242) for a two-year exploratory research project spanning June 1, 2025 through May 31, 2027. The project, titled "A Synaptogenic Adhesion Code for Myelin Specificity," investigates the molecular mechanisms underlying myelin formation and white matter abnormalities associated with autism spectrum disorder (ASD)...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Johns Hopkins University a Project Grant of $197,640 under the Mental Health Research Grants program (CFDA 93.242), effective September 1, 2025 through August 31, 2030. This award supports an early-career investigator's research into the functional consequences of schizophrenia-associated genetic variants in GRIA3, a gene encoding the GluA3 subunit of the AMPA receptor...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Washington University a $147,486 Project Grant under the Mental Health Research Grants program (CFDA 93.242) effective September 28, 2025, with a completion date of March 31, 2027. This research project, titled "Negative Symptoms, Cognition, and Functional Connectivity: Optimizing Transdiagnostic Relationships by Leveraging Advanced Techniques," aims to advance understanding of reduced motivation and...
The National Institute of Mental Health (NIMH) awarded a $763,894 Project Grant to The Washington University (Office of Sponsored Research Services) effective June 19, 2026, with completion targeted for April 30, 2031, under the Mental Health Research Grants program (CFDA 93.242). This award funds a comprehensive mechanistic investigation of ZNF292, a recently identified neurodevelopmental disorder (NDD) gene associated with autism spectrum disorder (ASD), intellectual disability, microcephaly, epilepsy, and other neurodevelopmental conditions. The research deliverables include molecular, cellular, structural, and functional characterization of ZNF292 requirements for cortical development using complementary experimental systems: human pluripotent stem cell (HPSC)-derived neurons carrying six pathogenic ZNF292 variants identified in affected patients, and conditional and non-conditional mouse knockout models. The project will produce scientific outputs documenting the downstream disease mechanisms and pathogenic consequences of ZNF292 deficiency and mutation across multiple biological levels, from transcriptional regulation and neuronal network function to circuit-level and behavioral outcomes. These research products are intended to guide development of evidence-based interventions for NDD-affected patients and advance understanding of how genetic variants contribute to neurodevelopmental pathology. The study employs both established cutting-edge workflows and innovative approaches, including temporally controlled reversal tools to investigate restoration of ZNF292 function in HPSC models.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $763.9k | 6/25/26 |