This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $287,000.00 to the University of Chicago to develop machine learning-based predictive models for forecasting clinical outcomes in psychosis-related disorders. The key objectives are to: Leverage electronic health record databases to build predictive models for treatment response, illness severity, medical comorbidities, and diagnostic transitions...
This federal Project Grant award of $508,500.00, funded by the National Institute of Mental Health (NIMH) under CFDA Program 93.242 Mental Health Research Grants, supports research to leverage electronic health records (EHR) and genomic data to develop machine learning-based predictive models for key clinical outcomes in psychosis-related disorders. The project aims to: 1) Use two independent EHR databases to build models predicting treatment response, illness severity, medical comorbidities,...
This $784,642 Project Grant awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program will support research at the New York Genome Center, Inc. (Nygc) to leverage electronic health records, dimensional phenotyping, and genomic analysis to develop predictive models for clinical outcomes in psychosis-related disorders. The key objectives are to: 1) Build machine learning models to forecast treatment response, illness severity, medical...
The National Institute of Mental Health (NIMH) awarded a $480,834 Project Grant (CFDA 93.242 - Mental Health Research Grants) to The Feinstein Institutes for Medical Research to leverage electronic health records (EHRs) and other data sources to develop machine learning-based predictive models for key outcomes in psychosis-related disorders. The 5-year project aims to build models to forecast treatment response, illness severity, medical comorbidities, and diagnostic transitions. The research...
This $2,694,945 Project Grant awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) funds research to identify cellular phenotypes related to the etiology, pathophysiology, and symptomatology of schizophrenia. The primary objectives are to: 1) replicate and expand on prior findings linking electrophysiological variables in patient-derived induced pluripotent stem cell (iPSC) models to clinical and cognitive phenotypes of...
This federal Cooperative Agreement award of $11,737,873 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) aims to develop clinical signatures for predicting key outcomes in young adults seeking mental health treatment. The project, titled "Phenotypes Reimagined to Define Clinical Treatment and Outcome Research (PREDICTOR)", will leverage data from electronic health records, audiovisual recordings of clinical interviews,...
This $3,093,740 federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support the "A Schizophrenia Extension Study for the NKI Rockland Sample II Project: An Open Resource of Multimodal Brain, Physiology & Behavior from a Community Lifespan Sample." The project will leverage the ongoing NIMH-funded NKI Rockland Sample II (NKI-RSII) study to create an open, multimodal dataset of brain...
This $2,516,931 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support a multidisciplinary research project to investigate the circuit-level mechanisms underlying auditory hallucinations (AH) in schizophrenia. The research team, led by the Trustees of Columbia University in the City of New York, will use a combination of human neuroimaging data, mouse models, and computational modeling to elucidate how...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $811,404 to The Trustees of Columbia University in the City of New York to conduct research on the neural circuit mechanisms underlying anticipatory anhedonia in schizophrenia. The goal of this research is to utilize a computational psychiatry approach to dissect the neural circuitry responsible for altered reward anticipation in individuals with...
This $812,950 Project Grant awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will fund the "PSYCHEMERGE: ADVANCING PRECISION PSYCHIATRY" research project. The project aims to develop a nationwide federated transfer-learning platform for generalizable and bias-aware algorithms, integrate advanced genomic analysis methods with electronic health record data to uncover novel biology informing precision psychiatry, and...