This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants (CFDA 93.242) program, provides $746,183 to the University of South Carolina to conduct a prospective, longitudinal study on neonatal autonomic nervous system (ANS) dysfunction as a predictor of autism spectrum disorder (ASD) in preterm infants. The study aims to: 1) evaluate preterm ANS dysfunction as an ASD-specific etiological mechanism, 2) examine how neonatal morbidities...
This federal Project Grant award of $794,931 from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), will fund a longitudinal study on the relationship between early parent-infant synchrony and later childhood outcomes among infants at genetic risk for ADHD or autism spectrum disorder (ASD). The study will leverage 3 existing cohorts of 326 infants previously enrolled in the PI's prior NIMH-funded studies, who will be followed from 6...
The National Institute of Mental Health (NIMH) awarded a $1,802,858 Project Grant (CFDA 93.242 Mental Health Research Grants) to the Scripps Research Institute in La Jolla, CA. The grant will fund research to map the functional impact of 72 high-confidence autism spectrum disorder and neurodevelopmental delay (ASD/NDD) risk genes using advanced in vivo genetic screening and whole-brain imaging technologies. This integrative approach aims to reveal how these genetic variants converge to produce...
This Project Grant award of $297,083 from the National Institute of Mental Health (CFDA 93.242 - Mental Health Research Grants) supports research to investigate caregiver perception of infant cries as an early marker of autism spectrum disorder (ASD). The key objectives are to: 1) replicate and extend prior findings on the association between caregiver cry perception and ASD outcomes, and 2) analyze longitudinal daylong recordings to assess the development of social contingency in...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), is focused on identifying and characterizing moderate effect size (MES) risk genes that contribute to Autism Spectrum Disorder (ASD) liability and presentation. The $844,917 award, which runs from July 1, 2025 to April 30, 2030, aims to pursue four specific objectives: Identify and characterize MES risk genes using rare variation stratified by common...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $251,250 to The Feinstein Institutes for Medical Research to study sex-dependent dysregulation of parvalbumin interneurons as a pathway to autism spectrum disorder (ASD). The key objectives are to: 1) Determine if the reduction in parvalbumin-expressing interneurons observed in male mice exposed in utero to anti-CASPR2 antibodies is associated with...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) is funding a research study to investigate the molecular mechanisms behind the sex-specific deficits observed in neurodevelopmental disorders like Autism Spectrum Disorder (ASD). The $431,750 award, active from May 1, 2025 to April 30, 2027, will support researchers at Rutgers, The State University of New Jersey in conducting studies using mouse models to...
This $509,310.95 Project Grant, awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program, aims to investigate longitudinal trajectories and social mechanisms of depression in adolescent girls with autism spectrum disorder (ASD). The grant will fund two secondary data analyses during the mentored K99 phase to map depression symptom trajectories in girls with ASD and typical development, as well as profile daily social experiences...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research to evaluate cognitive systems and psychopathology in autistic individuals who carry rare genetic variants associated with both autism spectrum disorder (ASD) and schizophrenia (SCZ). The $388,800 award will fund a study to remotely assess cognition and psychopathology in 400 ASD participants (200 with ASD+SCZ variants, 200 without) at two...
This federal Project Grant award, provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), will fund a $196,597 research project to investigate the information processing changes underlying a high-risk autism spectrum disorder (ASD) gene in rats. The project aims to determine the changes to the hippocampus and its communication with other brain regions in the context of this ASD gene, using advanced techniques such as automated...