This Project Grant award of $2,917,827 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will fund a hybrid effectiveness-implementation trial examining the use of an executive functioning intervention, "Unstuck and On Target," in community mental health settings. The study aims to evaluate the effectiveness and implementation of this autism-focused cognitive-behavioral intervention, compare it to a transdiagnostic...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $837,131 to Yale University to conduct research aimed at improving the inclusion of individuals with intellectual disability in autism neuroscience studies. The project will apply innovative technological and clinical approaches to collect neural and visual attention data, using electroencephalography (EEG) and eye-tracking, from 70...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support research into the neural substrates of autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD). The $367,708 award to the University of Southern California will use cutting-edge neuroimaging and advanced statistical modeling to investigate functional connectivity patterns in the brain's reward circuitry and how they...
This Project Grant award, valued at $739,843, was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The grant supports a 5-year research project from 2024 to 2029 entitled "The Role of the Exposome and Allostatic Load in Risk and Resilience to Youth Suicide Attempts." The project aims to quantify environmental risk factors (the "exposome") and physiological stress burden ("allostatic load") in...
This Project Grant award from the National Institute of Mental Health (NIMH) under CFDA Program 93.242 - Mental Health Research Grants provides $692,043 to support research on the role of presynaptic homeostatic plasticity in mental health disorders like autism and intellectual disability. The research aims to establish a mechanistic framework for how homeostatic regulation of neurotransmitter release and excitation/inhibition balance may relate to the genetic underpinnings of these mental...
This Project Grant award of $255,362 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) is for a study titled "Neural Mechanism of Reward Processing in Autistic Adolescents". The primary objective is to investigate differences in neural response to social and non-social reward processing between neurotypical and autistic youth, ages 10-15 years old. The study aims to: 1) Isolate differences in neural response to social...
This $769,284 project grant from the National Institutes of Health's National Institute of Mental Health will fund the development of new quantitative autism severity scores from existing instruments at John Carroll University from June 2022 through June 2025. Under the Mental Health Research Grants program (CFDA 93.242), the awardee will utilize multiple large datasets to apply modern psychometric approaches and create regression-adjusted, normative Social Responsiveness Scale-2 and Autism...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under CFDA 93.242 Mental Health Research Grants provides $844,917 to the Icahn School of Medicine at Mount Sinai to identify and characterize moderate effect size risk genes for Autism Spectrum Disorder (ASD). The key objectives are to: (1) identify and analyze moderate effect size risk genes using rare and common genetic variations; (2) investigate sex- and genetic ancestry-specific risk factors on the X...
The National Institute of Mental Health (NIMH) awarded a $857,060 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Rutgers, The State University of New Jersey. The grant funds a research study titled "Social-Ecological and Individual Determinants of the Course of Suicidal Ideation & Attempt Among African Americans from Early Adolescence to Young Adulthood". The study aims to: 1) identify trajectories of suicidal ideation and behavior among Black...
The National Institute of Mental Health (NIMH) awarded a $911,929 Project Grant (CFDA 93.242 Mental Health Research Grants) to the Scripps Research Institute to conduct research on the genetic basis of autism spectrum disorder and neurodevelopmental delay. The project, titled "Scalable Functional Analysis of Neuropsychiatric Risk Genes with Spatially Integrated In Vivo Perturb-Seq," aims to use advanced in vivo genetic screening and whole-brain imaging techniques to investigate how...
This Project Grant award, valued at $668,532, was issued by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program. The project aims to conduct a socioecological study of autism, suicide risk, and mental health care, utilizing multilevel analyses and community consultation to generate recommendations for suicide prevention among the autistic population.
The key products and services to be delivered through this award include:
Identifying clusters of socioecological factors associated with suicide risk among autistic youth and adults using national healthcare claims data and public/proprietary databases (Aim 1)
Evaluating socioecological factors related to mental health service receipt, dose, and delivery modality for autistic individuals with suicide behaviors and/or co-occurring mental health conditions (Aim 2)
Establishing community-supported recommendations to reduce suicide risk and improve mental health service delivery for autistic people, in collaboration with autistic stakeholders and focus groups (Aim 3)
The project is being led by the University of Florida, with sub-awards to the Morehouse School of Medicine for legal coding activities and the University of Utah for autistic community stakeholder engagement. The award period runs from August 1, 2024 to April 30, 2028.