The National Institute of Mental Health (NIMH) awarded a 5-year, $1,491,482 Project Grant (CFDA 93.242 - Mental Health Research Grants) to Brigham & Women's Hospital Inc. to investigate mechanism-based biomarkers of schizophrenia using neuroimaging. The project aims to characterize the relationship between increased extracellular water volume (free water), oxidative stress, neuroinflammation, and cognitive deficits in schizophrenia. It will leverage a validated animal model and analyze retrospective patient data to develop clinically-feasible analytic approaches for linking these biological factors to cognitive impairments. Additionally, the project includes a sub-award to Medprecis SA in Switzerland to conduct blood analysis, animal experiments, and data integration in support of the overall research objectives.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $0 | 4/8/25 | ||
| Not listed | $745.7k | 11/29/24 | ||
| Not listed | $745.7k | 11/29/24 |
Grant Number | Description | Subgrantee | Prime Award | Dollars Obligated (Click to sort descending) | Updated At (Click to sort ascending) |
|---|---|---|---|---|---|
GR0132132S01S | Medprecis SA | Project Grant R01MH136503 | $256.9k | 6/26/25 |