Project Grant R01MH136381
Award Date
9/25/24
Completion Date
6/30/29
Dollars Obligated
$679K
Federal Agency
National Institute of Mental Health
Federal Grant Program
93.242
Assistance Type
Project Grant
Place of Performance
Santa Cruz, CA 95064, USA
Similar Awards
This $1,255,890 Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants (CFDA 93.242) program, supports research at Cornell University to investigate the role of cortical GABAergic interneurons in the effects of the psychedelic drug psilocybin. The key objectives are to: 1) use cell type-specific electrophysiology to measure how the three major subtypes of GABAergic interneurons in the mouse medial frontal cortex respond to psilocybin...
This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $246,000.00 to The Trustees of Princeton University to investigate the brain mechanisms underlying the therapeutic potential of psilocybin. The research aims to: 1) examine the accelerated acquisition of motivated behavior and task performance after psilocybin administration, and 2) identify the cellular and brain-wide substrates driving...
This Project Grant award from the National Center for Complementary and Integrative Health (NCCIH), under the federal Research and Training in Complementary and Integrative Health program (CFDA 93.213), will fund a feasibility clinical trial to develop and evaluate a Psilocybin-Assisted Cognitive Behavioral Therapy (PA-CBT) protocol for treating major depressive disorder. The $236,250 award, granted on December 17, 2024, supports a 3-year study to refine and optimize the PA-CBT approach, and...
This federal Project Grant award for $708,511 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) will fund a mechanistic trial to elucidate the effects of psilocybin on neural activity in individuals with alcohol use disorder (AUD). The study aims to evaluate the impacts of high-dose versus low-dose psilocybin on AUD patients' neural response to negative affective stimuli and alcohol cues, as well as subsequent drinking...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), is funding research at the University of Oregon to investigate the polypharmacology and psychoplastogenic effects of psychedelic drugs using the C. elegans model organism. The overarching goal is to determine how representative psychedelic compounds, which primarily activate serotonin receptors, influence behavior and neuroplasticity in this invertebrate...
This federal Project Grant award of $692,043 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research to investigate the role of presynaptic homeostatic plasticity in mental health disorders such as autism and intellectual disability. The award recipient, The Regents of the University of California, San Francisco (UCSF), will conduct research to elucidate the molecular mechanisms underlying homeostatic plasticity and...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $649,965 to The Regents of the University of California, San Francisco (UCSF) from December 1, 2024 to October 31, 2029. The funding supports research to identify specific connections between the basolateral amygdala and ventral hippocampus that generate a biomarker of beta-frequency synchronization associated with mood and anxiety. The...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $781,119 to the University of California, San Francisco to conduct research on the neural population dynamics that represent unconditioned and conditioned stimuli in the ventral hippocampus. The 5-year project aims to leverage anatomical targeting, large-scale population recording, computational tools, and cell-type specific manipulation to...
This Project Grant award from the National Institute of Mental Health (NIMH), under the federal Mental Health Research Grants program (CFDA 93.242), will fund research to study the role of acetylcholine and cannabinoid signaling in the hippocampus and their impact on working memory and motivation. The $760,143 award to the University of Maryland, Baltimore will support animal model and human subject studies to investigate the anatomical and physiological mechanisms by which cannabinoid type 1...
The University of California, Davis (UC Davis) received a $1,414,340 Project Grant award from the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) to develop and deploy new molecular technologies that will enable the sub-cellular tagging and enrichment of proteins in activated subgroups of neurons in the brain. The goal is to link protein expression to neural function at a large and unbiased scale, which is not currently possible with existing...