Dynamic embedding time series models in functional brain imaging

Active Project Grant Awarded Last action

Award ID
R01MH133614
Recipient
Awarding agency
Obligated
$1,779,100

Award facts

Assistance listing
93.242 Mental Health Research Grants
Completion date 82% complete
Place of performance
Madison, WI 53715, USA

Award details come from USAspending.gov.

Description

Abstract
We will develop new large-scale dynamic embedding models of network data with a focus on dynamic connec- tivity matrices from non-stationary multivariate time series obtained from human functional magnetic resonance images (fmri). We propose to model brain networks as 2D curved surfaces, where the surface geodesics give connectivity information. Our approach will bypass the use of parcellations and more accurately evaluate the evolutionary dynamics of functional brain networks at the voxel level. We propose to build dynamically changing functional brain networks from a dataset with 1206 subjects from the human connectome project (HCP) database containing T1-weighted magnetic resonance images (MRI), diffusion MRI (dmri) and task and resting-state functional MRI (fmri). MRI and dmri will be used in conjunction with fmri in building more rened dynamic connectivity models. Using 243 pairs of twins in the HCP database, we will determine network phenotypes specic to behavior, cognition and their genetic associations. This study will provide the research community with the brain network heritability maps and as well as a versatile open-source toolbox of algorithms for modeling and visualizing dynamically changing large-scale brain networks.

Transactions

Action Obligated Date
Amendment $350,270
Amendment $350,270
Amendment $350,270
Amendment $364,145
Original award $364,145

Subawards

Subrecipient Amount Awarded
King Abdullah University Of Science And Technology Title: Dynamic embedding time series models in functional brain imaging Wisconsin PI: Professor Moo K. Chung KAUST Co-PI: Professor Hernando Ombao, Computer,… $0

Quick answers

Who received award R01MH133614?

R01MH133614 was awarded to University Of Wisconsin System by National Institute of Mental Health (National Institutes of Health) on September 7, 2023.

How much is award R01MH133614 worth?

$1,779,100 has been obligated on R01MH133614.

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