Project Grant R01MH123398
- Federal Grant Award Summary The Allen Institute received a $1.88 million Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded on March 13, 2026, with completion targeted for December 31, 2028. The project aims to develop a refined cellular atlas of the brainstem by employing single-cell transcriptomic profiling, spatial transcriptomic profiling, and neuronal projection mapping. The deliverables include...
- The National Institutes of Health (NIH) Office of the Director awarded a $1,271,280 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to the Allen Institute in Seattle, WA. The award, spanning September 2024 to September 2027, aims to develop two "exa-scale" (extremely high-throughput) tissue readout methods to transform the study of the brain. The first method will enable highly multiplexed molecular mapping of individual proteins across entire brains at the...
- This $2,576,654 Project Grant awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support the development of a cloud-based software platform and advanced computational pipelines to harmonize and integrate spatial transcriptomics data for the construction of a spatially resolved brain atlas. Key objectives of the 3-year project include: 1) Creating a cloud-based platform to standardize the analysis and visualization of...
- This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $2,415,243 to The Broad Institute, Inc. to develop a scalable, cloud-based framework for multi-modal mapping across single neuron omics, morphology, and electrophysiology. The framework aims to enable integrative, data-driven characterization of brain cell types, leveraging federated Brain Initiative resources and community engagement....
- Federal Cooperative Agreement Summary The Allen Institute received a $2.04 million Cooperative Agreement from the National Institute of Neurological Disorders and Stroke (NINDS) under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372) to develop and demonstrate advanced light-microscopy-based connectomics (LICONN) technologies for mapping brain cell connectivity at multiple scales. The award, effective August 11, 2025...
- The University of Minnesota was awarded a $3,972,414 Project Grant from the National Institute of Neurological Disorders and Stroke within the Department of Health and Human Services to develop an electro-optical multiphoton microscope. The microscope will leverage advances in electro-optical beam deflection to enable random-access multiphoton interrogation of neurons and synapses with sub-microsecond access times. This will allow neuroscientists to collect the simultaneous recordings needed...
- Federal Cooperative Agreement Summary The National Institute of Mental Health (NIMH) awarded the Allen Institute a Cooperative Agreement valued at $8.68 million under the Mental Health Research Grants program (CFDA 93.242) beginning May 1, 2025 and concluding February 28, 2030. The award funds the development of an Enhancer Adeno-Associated Virus (AAV) Toolbox designed to create, screen, characterize, and distribute a comprehensive set of viral tools capable of targeting specific cell classes...
- Purdue University was awarded a $1,304,216 Project Grant by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) to develop and test a new platform for high-density 3D electrophysiology and two-photon calcium imaging in freely moving animals. The goal is to enable simultaneous recording of millisecond electrical dynamics and spatial mapping of neural circuit activity during natural behaviors to better understand how the brain processes...
- Federal Grant Award Summary The Child Mind Institute Inc. received a $578,500 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded May 1, 2025, with completion targeted for February 29, 2028. The project develops computational tools to integrate brain microstructure with functional dynamics in human and non-human primates. The primary deliverables include: (1) extended BrainBuilder software to reconstruct...
- The National Institutes of Health (NIH) awarded a $1,385,000 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to the Allen Institute, a non-profit research organization, to develop novel techniques for measuring the input-output operations of individual neurons in the mouse cortex. The project aims to overcome challenges in understanding how neurons in the mammalian brain transform their synaptic inputs into outputs, which is critical for designing effective brain-machine...
The Allen Institute was awarded $883,701 under a Project Grant from the National Institute of Mental Health to develop a robust, low-cost platform for electron microscopy (EM) connectomics. The goal is to establish a widely adoptable system centered on an open source serial sectioning robot implementing a novel collection approach. This will enable EM volumes ranging from 50mm on a side to over 1 cubic millimeter to be routinely sectioned and imaged, making EM connectomics tools available to more neuroscientists. The project will create data sets testing the flexibility and robustness of the approach in the final year. The grant is part of the National Institute of Mental Health's Mental Health Research Grants program (CFDA #93.242), which supports basic and clinical research to transform understanding and treatment of mental illnesses.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $883.7k | 7/15/21 |