Project Grant R01MD020650
- Federal Grant Award Summary Howard University received a $424,875 Project Grant from the National Institute on Minority Health and Health Disparities (NIMHD) under the Minority Health and Health Disparities Research program (CFDA 93.307), awarded September 19, 2025, with completion scheduled for June 30, 2027. This exploratory research project focuses on understanding the pathobiology of metabolic dysfunction-associated steatotic liver disease (MASLD) in African Americans with type 2 diabetes...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded $742,456 to the Regents of the University of Minnesota through the Biomedical Research and Research Training program (CFDA 93.859) to support a five-year research initiative on genetic inference and prediction in diverse, multi-ancestry cohorts. Commencing September 1, 2025, and concluding June 30, 2030, this project will develop statistical tools and methodologies to address the challenges...
- Federal Project Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded the Regents of the University of Michigan a $776,863 Project Grant on September 15, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to conduct multi-ancestry whole genome sequencing analyses of metabolic dysfunction-associated steatotic liver disease (MASLD). The five-year research project, concluding August 31, 2030, aims...
- Federal Grant Award Summary Rush River Research Corp received a $4.15 million Project Grant from the National Institute for Minority Health and Health Disparities (NIMHD) under the Minority Health and Health Disparities Research program (CFDA 93.307), awarded on September 18, 2025, with completion targeted for May 31, 2027. The award funds development of a modernized, culturally sensitive Family Health History (FHH) software tool designed to address health disparities among African Americans,...
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded the Regents of the University of Minnesota a $319,550 Project Grant effective September 15, 2025, through August 31, 2030, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The research focuses on defining choline metabolism in metabolic health, with emphasis on how impaired choline catabolism contributes to metabolic-associated liver...
- Federal Project Grant Award Summary The National Institute on Minority Health and Health Disparities (NIMHD) awarded The Washington University a $403,212 Project Grant on September 5, 2025, under the Minority Health and Health Disparities Research program (CFDA 93.307) to support a career development initiative focused on fetal growth restriction (FGR) among Black women. This K01 Career Development Award funds translational research investigating the relationship between maternal serum...
- Federal Project Grant Award Summary The University of Minnesota received a $333,290 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective March 1, 2026, through February 28, 2031. This award funds the development of a comprehensive analytical framework for integrating high-throughput biomedical data across multiple sources, dimensions, and patient cohorts. The research deliverables...
- Federal Grant Award Summary The National Institute on Minority Health and Health Disparities (NIMHD) awarded a $2.31 million Project Grant to the University of California, San Francisco on September 13, 2025, under the Minority Health and Health Disparities Research program (CFDA 93.307). The study, which extends through June 30, 2030, investigates hypertension (HTN) care retention and cardiovascular disease (CVD) risk among people with HIV (PWH) receiving care at safety net clinics. Using an...
- Federal Grant Award Summary The Regents of the University of Minnesota received a $174,528 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective September 1, 2025 through August 31, 2030. This award supports reverse translational research to identify novel treatment targets for atrial myopathy, a condition involving structural, mechanical, or electrophysiological changes in the atria that may...
- Federal Project Grant Award Summary The National Institute on Minority Health and Health Disparities (NIMHD) awarded the University of New Mexico Health Sciences Center a $467,489 Project Grant on July 29, 2025, under the Minority Health and Health Disparities Research program (CFDA 93.307) to conduct comprehensive research on interhospital disparities in out-of-hospital cardiac arrest (OHCA) care and outcomes. The project, led by Dr. Ryan Huebinger and extending through June 30, 2030, will...
The Regents of the University of Minnesota received a $701,978 Project Grant award from the National Institute on Minority Health and Health Disparities (NIMHD) under the Minority Health and Health Disparities Research program (CFDA 93.307), effective June 8, 2026, with completion targeted for November 30, 2030. The research initiative investigates the role of the RS142619613 genetic variant within the YY1 gene in the pathogenesis of metabolic dysfunction-associated fatty liver disease (MAFLD) and hyperglycemia, with particular focus on African American populations. The university will conduct mechanistic studies examining how this variant augments the YY1-miR-23b/27b/24 regulatory axis to promote hepatic lipogenesis and gluconeogenesis while exacerbating hepatic insulin resistance and metabolic dysfunction. The project aims to elucidate underlying genetic and molecular mechanisms driving disparities in Type 2 Diabetes and MAFLD among African Americans, with the long-term goal of identifying YY1 and miR-23b/27b/24 as potential therapeutic targets. Deliverables will include peer-reviewed scientific findings, mechanistic data characterizing the variant's effects on hepatic metabolism, and evidence supporting therapeutic intervention development. This research aligns with NIMHD's mission to support basic and clinical research that improves minority health outcomes and reduces health disparities across underserved populations.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $702.0k | 6/11/26 |