The federal Project Grant award R01LM014698, totaling $608,586.00, was awarded by the National Institute of Environmental Health Sciences (NIEHS) under the Medical Library Assistance (CFDA 93.879) program. The grant aims to develop a better understanding of how data errors can impact bioinformatics software and analytical results, and to create algorithms and strategies to protect against such errors. The University of Maryland, College Park is the primary awardee and will conduct the research...
This federal Project Grant award for $1,312,212 from the National Institute of Environmental Health Sciences (NIEHS) under the Medical Library Assistance (CFDA 93.879) program will support research to develop an advanced DNA language model. The primary goal is to use natural language processing techniques to better understand the role and functionality of DNA sequences, especially non-coding regions, which could lead to advancements in areas like genetic testing and personalized medicine. The...
This federal Project Grant award for $338,538 was provided by the National Institute of Environmental Health Sciences (NIEHS) under the Medical Library Assistance (CFDA 93.879) program. The grant aims to develop a novel deep learning framework called DeepGene to predict spatial cell-type clusters in whole-brain spatial transcriptomics datasets. The research will create a comprehensive parcellation/atlas of the adult mouse brain shared across multiple mouse brain samples. The goal is to integrate...
This federal Project Grant award, funded by the National Institute of Environmental Health Sciences (NIEHS) under the Medical Library Assistance (CFDA 93.879) program, aims to develop and validate a novel informatics framework to extract computable population, intervention, comparison, and outcome (PICO) elements and summarize them from publications of interventional and observational studies. The total funding amount is $391,388.00, with an award date of September 18, 2024 and an ultimate...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, provides $558,380 to the Icahn School of Medicine at Mount Sinai to develop an integrated biomedical knowledgebase and geospatial data science ecosystem called GEOSPACE. The key products to be delivered include: A geospatial database of curated exposure datasets (GSEDB) that will index multiple data streams on high priority environmental...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) totaling $502,479 aims to measure the impact of research data reuse on diversity and scientific innovation, and identify synergistic data-method-researcher combinations to spur scientific discovery. The project will construct knowledge graphs connecting research objects like publications, code, and datasets to provide insights into how...
This Project Grant awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) will support research to develop improved computational methods for human gene annotation. The $387,500 award to The Johns Hopkins University will fund efforts to adapt and expand their existing StringTie software system, a genome-guided transcriptome assembler, to process large-scale RNA sequencing data and build a comprehensive,...
The National Human Genome Research Institute (NHGRI) awarded a $1,033,069.24 Project Grant (CFDA 93.172 - Human Genome Research) to The Johns Hopkins University to develop novel statistical methods for data integration across disparate datasets in genetic and epidemiologic studies. The project aims to: Create a framework for building generalized linear models using detailed covariate data from a main study while incorporating summary statistics from an external study, with applications to...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $424,264 in funding to the Regents of the University of Michigan from June 1, 2025 to May 31, 2030. The funding will support the development of advanced quantitative analysis methods for long-read RNA sequencing, both at the bulk and single-cell level. The goal is to enable deeper investigations of gene isoforms and their...
This $249,943 Project Grant award from the National Institutes of Health's National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program supports the research and development of an adverse outcome pathway-focused mechanistic inference tool for 'omics data using semantic knowledge graphs. The key products and services to be delivered through this one-year award include: Improving statistical models to better quantify adverse outcome pathway...