Project Grant R01HS030234

The Vanderbilt University Medical Center (VUMC) has been awarded a $490,523 Project Grant under the Research on Healthcare Costs, Quality and Outcomes (CFDA 93.226) program administered by the Agency for Healthcare Research and Quality (AHRQ). This 5-year grant aims to adapt and implement risk-stratified penicillin allergy evaluation and delabeling in outpatient surgical, transplant, and obstetric settings. The key objectives are to: 1) measure the efficacy, barriers, and facilitators of outpatient antibiotic allergy assessment across diverse clinical environments, 2) design and pilot patient-centered penicillin allergy self-assessment tools, and 3) implement penicillin allergy risk assessment in outpatient pre-surgical care. Successful completion of these research aims will produce new tools and models to enhance outpatient implementation of penicillin allergy management, ultimately improving the use of first-line antibiotics and reducing related healthcare challenges.