Project Grant R01HL180859
- The National Heart, Lung, and Blood Institute awarded Seattle Children's Hospital, doing business as Seattle Children's Research Institute, $1,839,440 on August 5, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to investigate how heavy chain hyaluronan and TSG-6 modulate lung inflammation during respiratory syncytial virus (RSV) infection. The research examines the extracellular matrix's role in RSV pathogenesis, focusing on age-dependent inflammation in young children....
- The National Heart, Lung, and Blood Institute awarded Seattle Children's Hospital $930,637 under the Cardiovascular Diseases Research program (CFDA 93.837) on September 1, 2026, to conduct PROSPER (Pulmonary Recovery and Outcomes After Severe Pediatric Respiratory Illness), a multicenter prospective longitudinal cohort study examining how impaired pulmonary function contributes to physical and health-related quality-of-life morbidity among children surviving acute respiratory failure. The...
- The National Heart, Lung, and Blood Institute (NHLBI) awarded Boston Children's Hospital $171,600 on September 1, 2026, under CFDA 93.837 (Cardiovascular Diseases Research) to support career development and mentored research in pediatric obstructive sleep apnea diagnostics. The award funds the recipient investigator's training in three areas: predictive modeling and machine learning, advanced physiological signal analysis, and implementation science for translating research into clinical...
- The National Heart, Lung, and Blood Institute awarded the University of North Carolina at Chapel Hill $166,248 on September 26, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837) to conduct research triangulating causal effects of sleep, inflammation, and cardiometabolic disease. The research will identify oxylipin biomarkers associated with sleep problems—including insomnia, sleep apnea, and short sleep duration—and their relationship to cardiometabolic disease. The study...
- The National Heart, Lung, and Blood Institute awarded Emory University $100,228 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to conduct longitudinal research examining associations between sleep health, protective factors against psychosocial adversity, and stress-related biomarkers including allostatic load and epigenetic age acceleration. The project analyzes multidimensional sleep health—encompassing regularity, satisfaction, alertness, timing,...
- The National Heart, Lung, and Blood Institute awarded Brigham & Women's Hospital Inc. $353,776 under the Cardiovascular Diseases Research program (CFDA 93.837) on September 20, 2025. The award funds investigation of place-based factors contributing to sleep health disparities in the United States. The research links nationwide public health surveillance data to neighborhood-level factors using geographic information science to test whether individual-level and place-based factors...
- Federal Project Grant Award Summary New York University School of Medicine received a $254,250 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded September 15, 2025, with completion targeted for August 30, 2027. This research project examines neighborhood context factors and their influence on sleep health disparities among first and second-grade children, primarily Black students in New York City....
- The National Heart, Lung, and Blood Institute awarded Children's Research Institute $1,818,088 on July 15, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to investigate how postnatal hypoxemia—reduced blood oxygen levels present in cyanotic congenital heart disease—impacts cardiac maturation and surgical recovery outcomes in pediatric patients. The project will examine the interaction between hypoxemia, myocardial immaturity, and postoperative complications through...
- The National Heart, Lung, and Blood Institute awarded Emma Pendleton Bradley Hospital $175,175 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop and implement a digital sleep intervention for preschoolers in foster care. The award funds development, pretesting, and evaluation of Nurturing Sleep, a trauma-informed digital public-health-level sleep intervention administered to foster caregivers of children ages 36–71 months. Aim 1 involves...
- The National Institute of Child Health and Human Development awarded Seattle Children's Hospital $5,031,656 on September 30, 2025, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct longitudinal research examining how early life social determinants and sex-specific pubertal pathways contribute to the development of adolescent chronic pain. The project follows approximately 415 mother-child dyads across four sites in the United States through age 14,...
The National Heart, Lung, and Blood Institute awarded Seattle Children's Hospital $1,736,235 on August 15, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to investigate sleep health and its relationship to childhood systemic lupus erythematosus (CSLE) symptoms within the sociocultural and neighborhood contexts of affected youth. The research examines associations between sleep health dimensions—including duration, efficiency, regularity, and daytime sleepiness—and CSLE disease manifestations such as pain, fatigue, anxiety, and depression. Prior pilot work in a diverse CSLE youth sample demonstrated that inadequate sleep duration, irregular sleep timing, and poor sleep efficiency predicted worse next-day pain and were associated with increased fatigue, anxiety, depressed mood, and lower health-related quality of life. The study addresses a gap in pediatric rheumatology; sleep remains a modifiable behavior not routinely assessed in clinical care. The research prioritizes non-Hispanic Black and Hispanic youth, who experience both greater sleep health disparities and elevated CSLE disease prevalence, potentially compounding symptom severity and access-to-care barriers. Seattle Children's Research Institute, doing business as Seattle Children's Hospital, performs the work in Seattle, Washington. The period of performance runs through May 31, 2028. The award is structured as a Project Grant, the standard NIH assistance type for investigator-initiated research.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.7m | 8/20/26 |