This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) will fund a 16-site cluster-randomized trial in Uganda to evaluate the impact of a peer-led navigation strategy on improving tuberculosis (TB) and HIV treatment adherence and outcomes. The $646,561 award will support the development and implementation of a multi-component peer-navigation intervention that includes task-shifting TB education and...
This $565,250 federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) will support a longitudinal study to characterize the effects of host-microbiome interactions on pulmonary function in adults with and without HIV in Botswana. The research team at Duke University will collect clinical data, along with saliva, sputum, and stool samples from 500 adults (250 with HIV, 250 without) over 24 months....
This federal Project Grant award of $743,698 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) aims to characterize the burden, severity, and phenotypic presentation of post-tuberculosis (TB) lung disease (PTLD) and its association with interleukin-6 (IL-6) signaling pathways in TB patients with and without HIV. The award will leverage an ongoing NIAID and Indian government-funded study in India...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) provides $100,558 to Stellenbosch University in South Africa to conduct research on cardiovascular abnormalities in people living with HIV (PLWH) before and after initiating antiretroviral therapy (ART). The research will utilize cardiovascular magnetic resonance imaging (CMR) to characterize early cardiovascular changes, measure...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH), under the Cardiovascular Diseases Research program (CFDA 93.837), will support research to determine the pathophysiological mechanism and potential treatment of HIV-associated chronic obstructive pulmonary disease (COPD). The total award amount is $472,980.00 with a project period from September 1, 2024 to May 31, 2028. The primary aim is to investigate how HIV...
This $246,000 Project Grant award, made by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to investigate the role of lung repair and regeneration pathways in tuberculosis (TB). The key objectives of this research project are to determine the functional role of the bone morphogenetic protein (BMP) signaling pathway in Mycobacterium tuberculosis (MTB) control and TB reactivation, as...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) provides $1,185,782 to the University of Alabama at Birmingham (UAB) to establish a global research resource for studying tuberculosis (TB) in human lung tissue. The key products and services funded under this 5-year award include: (1) conducting pathological, cellular, structural, and genetic analysis of resected active TB and post-mortem...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $760,760 to the Augusta University Research Institute, Inc. (doing business as Georgia Health Sciences) to conduct research on novel mechanisms of HIV-associated pulmonary vascular disease. The key products and services to be delivered under this grant include investigating whether HIV-encoded proteins, particularly the HIV-Tat...
This federal Project Grant award, titled "LOW CARDIORESPIRATORY FITNESS AND CHRONOTROPIC INCOMPETENCE INHIV: RISK FACTORS, CARDIOVASCULAR IMPLICATIONS, AND EXERCISE TRAINING AS TREATMENT", was provided by the National Heart Lung and Blood Institute (NHLBI) under the Cardiovascular Diseases Research Program (CFDA 93.837). The $197,748 award, effective June 1, 2024 through May 31, 2029, will support research conducted by The Regents of the University of California, San Francisco (UCSF)...
This $641,960 federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), will support research conducted by the Augusta University Research Institute, Inc. (doing business as Georgia Health Sciences) to investigate the mechanisms by which HIV-associated proteins contribute to the development of hypertension, a leading risk factor for cardiovascular disease, in people living with HIV. The 4-year...