Project Grant R01HL174911

Award Date 8/6/24
Completion Date 5/31/28
Dollars Obligated $2.4M
Federal Grant Program
93.837
Assistance Type
Project Grant
Place of Performance
Columbus, OH 43210, USA
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The key goals of the research are to: 1) Determine how the potassium channel interacting protein KCHIP2 regulates the expression of the JNK2 kinase, and 2) Explore how the KCHIP2-JNK2 axis promotes SCD in HF. The research will test therapeutic interventions involving overexpression of KCHIP2 and/or inhibition of JNK2 as novel anti-arrhythmia strategies for HF patients. This 4-year award began on August 6, 2024 and is scheduled for completion by May 31, 2028.

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