The National Heart Lung and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), awarded a $727,080 Project Grant to the University of South Carolina to investigate the neurogenic mechanisms underlying the relationship between psychosocial stress, postpartum cardiovascular disease, and postpartum depression. The 4-year research project aims to delineate how stress-induced mitochondrial dysfunction in the medial prefrontal cortex contributes to postpartum...
This Project Grant award of $602,358, provided by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), aims to assess the contribution of epigenetics to cardiovascular risk in African American women. The project will identify epigenetic biomarkers of cardiovascular disease and its environmental determinants, and evaluate if these biomarkers can contribute to risk prediction assessments. The research will be conducted by the...
This Project Grant award of $696,470.00 from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports research at the University of Denver to investigate the relationship between prenatal maternal sleep and offspring cardiovascular disease risk. The research aims to: 1) examine how prenatal maternal sleep trajectories predict maternal biological pathways like inflammation and stress, 2) assess how prenatal maternal sleep impacts offspring growth,...
The University of Pittsburgh was awarded a $705,915 Project Grant from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) to conduct the "Integrative Model of Metabolomics, Equol and Atherosclerotic Cardiovascular Disease (IMMEA)" study. The study aims to (1) determine the association of equol-producing status with atherosclerotic cardiovascular disease (ASCVD) and (2) build predictive models of ASCVD from equol, marine omega-3 fatty acids,...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under CFDA 93.837 - Cardiovascular Diseases Research aims to evaluate factors driving delays in the diagnosis of peripartum cardiomyopathy (PPCM), a form of heart failure that occurs in the weeks or months after childbirth. The $601,075 award will fund a mixed-methods study to determine patient-reported, provider, and health system factors contributing to delayed PPCM diagnosis, with a focus on understanding...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Federal Grant Program for Cardiovascular Diseases Research (CFDA 93.837), provides $123,104 to Emory University to conduct research on factors contributing to cardiovascular disease (CVD) comorbidities in persons living with HIV (PWH). The key objectives are to: 1) assess relationships between the metabolome, lipidome, HIV reservoir, and subclinical CVD, analyzing differences by sex; and 2) determine...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) provides $234,000 to the University of Colorado-Denver to investigate weight loss maintenance following a one-year dietary intervention. The goal is to compare post-intervention adherence and clinical outcomes between standard caloric restriction and two time-restricted eating approaches, as well as generate pilot data on gut microbiota predictors...
The National Heart, Lung, and Blood Institute (NHLBI) awarded Emory University a $127,645 five-year Project Grant (CFDA 93.837 Cardiovascular Diseases Research) starting on August 15, 2024. The goal of this K24 Midcareer Investigator Award in Patient-Oriented Research is to enhance Dr. Miriam Vos's ability to train, mentor, and support new investigators in patient-oriented research on early cardiometabolic disease in children. The research aims to understand the physiological changes leading...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) will provide $171,450.00 to investigate the biological mechanisms linking excess body fat (adiposity) and elevated blood lipid levels, and their combined impact on cardiovascular disease risk. The research, led by Dr. Dron, a computational geneticist, aims to: 1) measure how adiposity interacts with genetic variants to influence lipid levels, 2)...
This $132,410 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) will provide protected time for Dr. Cheryl Anderson, a mid-career clinical investigator, to recruit and mentor a diverse group of trainees in clinical cardiovascular epidemiology and health equity research. The award will support two new areas of research: 1) integrating global policy and strategy into multilevel interventions to improve...