Project Grant R01HL172349

Award Date 5/1/25
Completion Date 4/30/30
Dollars Obligated $671K
Federal Grant Program
93.837
Assistance Type
Project Grant
Place of Performance
Dallas, TX 75390, USA
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The key research objectives are to determine the effects of chronic lower leg heating on 1) maternal vascular function and surrogate markers of hypertensive disorders of pregnancy, and 2) sympathetic vasoconstriction and blood pressure. Researchers will measure vascular function, sympathetic activity, and related biomarkers before and during the 16-week intervention period. Findings from this project are expected to provide insights into the mechanisms by which chronic lower leg heating can improve vascular and neural function, potentially reducing the risk of hypertensive disorders in high-risk pregnant women. The award has a project period from May 1, 2025 to April 30, 2030.

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