Multifidelity and multiscale modeling of the spleen function in sickle cell disease with in vitro, EX vivo and in vivo validations

Ended Project Grant Awarded Last action

Award ID
R01HL154150
Recipient
Awarding agency
Obligated
$6,632,052

Award facts

Assistance listing
93.837 Cardiovascular Diseases Research
Completion date
Originally
Funding
  • $5,969,051.00 Federal
  • $663,001.00 Non-federal
Place of performance
Rhode Island, USA

Award details come from USAspending.gov.

Transactions

Action Federal Non-federal Date
Amendment $0 $0
Amendment Digital twins of the spleen to accelerate the design and development of new therapies in sickle cell disease - the spleen clears the blood by removing the… $669,068 $0
Amendment $669,068 $0
Amendment Digital twins of the spleen to accelerate the design and development of new therapies in sickle cell disease - the spleen clears the blood by removing the… $0 $0
Amendment $0 $0
Amendment $636,323 $0
Amendment $650,173 $0
Amendment $650,173 $0
Amendment $663,001 $0
Amendment $663,001 $0
Amendment $663,001 $663,001
Original award $705,243 $0
Show all 12

Subawards

Subrecipient Amount Awarded
Universite Paris Cite We will collect blood samples from patients with Sickle Cell Disease (SCD) undergoing splenectomy, or patients undergoing left spleno-pancreatectomy for… $140,940
University Of Georgia Research Foundation, Inc. The Co-PI at UGA will be responsible for 1. Develop and validate pharmacokinetic/pharmacodynamic models to simulate sickling kinetics of RBCs with different… $101,773
Massachusetts Institute Of Technology We will conduct a comprehensive and integrated clinical, microfluidic, and computational investigation to explore the effects and mechanisms of SCD drugs used… $200,340
Massachusetts Institute Of Technology The overall project led by Brown University aims at formulating and validating a new multiscale, multifidelity model based on atomistic-mesoscopic-continuum… $64,446

Quick answers

Who received award R01HL154150?

R01HL154150 was awarded to Brown University by National Heart Lung and Blood Institute (National Institutes of Health) on August 19, 2020.

How much is award R01HL154150 worth?

$6,632,052 has been obligated on R01HL154150: $5,969,051 in federal funding and $663,001 in non-federal funding.

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