Project Grant R01HG013679

Award Date 9/19/24
Completion Date 6/30/28
Dollars Obligated $744K
Federal Grant Program
93.172
Assistance Type
Project Grant
Place of Performance
Cambridge, MA 02138, USA
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  1. Develop "Single-Cell Expansion Genomics" techniques that combine sample expansion with modern single-cell methods to enable high-throughput, multi-modal epigenomic measurements without specialized microfluidics.

  2. Integrate expansion with multiplexed spatial imaging approaches in "Spatial Expansion Genomics" to reveal the nanoscale organization of the epigenome.

The Broad Institute has received a $XXX,XXX sub-award to help develop the expansion microscopy protocols and gel chemistries needed to support these Expansion Genomics technologies. This award aims to significantly advance genomic research and its applications to human health through innovative epigenomic analysis methods.

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