Project Grant R01HD121701
- Federal Grant Award Summary The University of California, San Diego received a $126,462 Project Grant from the National Institute of Child Health and Human Development under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective September 1, 2025, through June 30, 2028. The award supports fundamental neuroscience research investigating the neural circuit mechanisms underlying pubertal timing, with a specific focus on characterizing rfamide-related peptide...
- Federal Grant Award Summary The University of California, San Diego received a $711,432 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective May 15, 2026, with completion expected February 28, 2031. This award supports research investigating the molecular mechanisms of meningomyelocele (spina bifida), the most common central nervous system congenital...
- Federal Grant Award Summary The University of California, San Diego received a $452,000 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), awarded August 1, 2025, with completion by July 31, 2027. This research project aims to identify a cellular immune signature unique to clinically-significant villitis of unknown etiology (VUE), a chronic inflammatory placental lesion...
- Federal Grant Award Summary The University of California, San Diego received a $151,040 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective January 25, 2026 through July 31, 2027. This research project investigates the effects of rare damaging mutations in Transforming Growth Factor-Beta (TGFB) latent complex proteins, specifically Fibronectin 1 (FN1) and...
- Federal Grant Award Summary The University of California, San Diego received a $877,852 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) on August 19, 2025, with completion targeted for July 31, 2027. This research project delivers epidemiological and clinical investigation services examining the prevalence, risk factors, and clinical progression of uterine...
- Federal Project Grant Summary The National Institute of Child Health and Human Development (NICHD) awarded University of California, San Diego $566,573 on August 1, 2025, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct an individually randomized controlled trial evaluating point-of-care screening and treatment for Chlamydia trachomatis (CT) infection to prevent preterm birth among asymptomatic pregnant women in Botswana. This five-year project...
- Federal Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded a $702,556 Project Grant to the University of California, Davis on May 15, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865). The research initiative, titled "Modeling Neurodevelopmental Risk of Imbalanced Micronutrient Supply in Cerebral Organoids," will be conducted through February 28, 2031. The project delivers investigator-initiated...
- Federal Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded a $163,050 Project Grant to the University of Chicago on November 22, 2025, under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award extends through June 30, 2029, and supports a research initiative titled "Leveraging Enhanced Phenotyping and Causal Inference Approaches to Investigate the Effect of Maternal Medication Exposures on Child...
- Federal Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded Columbia University's Health Sciences Division a Project Grant of $452,375 under the Child Health and Human Development Extramural Research program (CFDA 93.865) for research on neurosteroid regulation of placental inflammation. The award period runs from August 1, 2025 through July 31, 2027. The research will investigate the role of allopregnanolone (ALLO), a naturally occurring...
- Federal Project Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded Columbia University's Health Sciences Division a $719,141 Project Grant (CFDA 93.865: Child Health and Human Development Extramural Research) on August 11, 2025, to conduct a longitudinal study leveraging in vitro fertilization (IVF) to identify prenatal programming effects independent of shared maternal-child genes. The research will test the Developmental Origins of Health and...
Federal Grant Award Summary The University of California, San Diego received a $657,971 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), awarded on May 15, 2026, with a completion date of February 28, 2031. The award funds research investigating the role of dopamine in neuroimmunoendocrine mechanisms underlying spontaneous preterm birth (SPTB). The research integrates pathological, physiological, and psychological domains to establish neuroimmunoendocrine pathways as critical modulatory links between maternal mental state, immune imbalance, and SPTB risk. The grant supports three specific research aims: determining whether central dopaminergic activity mitigates inflammation-induced preterm birth in murine models; defining predictive neuroimmunoendocrine trajectories of SPTB and placental inflammatory signatures in longitudinal human pregnancies; and determining dopamine's effects on the human maternal-placental interface by comparing term and preterm births. The research employs both preclinical neuromodulation techniques and clinical evaluations incorporating psychological assessments, immunological markers, and placental pathology analysis to develop robust prediction tools and identify therapeutic intervention targets for SPTB prevention.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $658.0k | 5/14/26 |