Project Grant R01HD119838
- The Trustees of Columbia University in the City of New York (Columbia University), through its Health Sciences Division, was awarded a $445,009 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The grant's objective is to develop approaches for introducing developmentally-relevant inputs and reading out neuronal activity in human brain organoids to...
- This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $152,226 to The Trustees of Columbia University in the City of New York to support research on the molecular mechanisms of Hedgehog (Hh) signal transduction in Drosophila. The research aims to elucidate how the Hh signaling pathway regulates the activity of the conserved transcription factors...
- This Project Grant award of $248,994 was provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), which administers the Child Health and Human Development Extramural Research Federal Grant Program (CFDA 93.865). The award will fund research by the Washington University in New York, NY to investigate the mechanisms by which histone mutations affect chromatin structure, gene expression, and neural differentiation during development. The goal is to...
- The Trustees of Princeton University was awarded a $458,236 Project Grant by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The purpose of this 5-year grant, awarded on August 9, 2025, is to investigate the mechanisms responsible for the formation and selection of oocytes (egg cells) within the germline cysts of female mice. The researchers will develop novel genetically-encoded...
- The Trustees of Columbia University in the City of New York received a $452,375 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research Federal Grant Program (CFDA 93.865). The award, effective from August 1, 2025 to July 31, 2027, supports research to investigate the reciprocal interactions between placental neurosteroid allopregnanolone and placental inflammatory...
- The Project Grant award titled "Asymmetric RNA Segregation in Neural Stem Cells" was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The $392,004 grant will support research at the University of Washington to identify and characterize asymmetrically segregating RNA molecules in fly neural stem cells, with the goal of understanding how RNA partitioning contributes...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is providing $127,145 to The Trustees of Princeton University to conduct research dedicated to unraveling the regulatory mechanisms governing chromatin organization and gene transcription during neural development in the Drosophila model organism. The primary focus is on understanding how...
- The Trustees of Columbia University in the City of New York received a $435,475 Project Grant from the National Human Genome Research Institute (NHGRI) under the "Human Genome Research" (CFDA 93.172) program. The grant funds the development of novel machine learning methods for analyzing spatial transcriptomic data without the need for paired single-cell data. The proposed computational toolbox will enable the characterization of diverse cell states and their spatial dynamics through...
- This federal Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), is focused on identifying novel noncoding genetic mechanisms that contribute to developmental disorders. The $499,055.48 award, with a project period from November 1, 2024 to October 31, 2027, will fund research led by Dr. Chelsea Lowther at the Icahn School of Medicine at Mount...
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $133,401 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the Fred Hutchinson Cancer Center, located in Seattle, WA. The grant, awarded on September 1, 2025, is intended to develop computational models that can identify the sequence of changes a cell undergoes during differentiation and maturation, and compare changes in gene expression...
The Trustees of Columbia University in the City of New York was awarded a $638,625.00 Project Grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) on August 21, 2025. The project, titled "In Vivo Regulation of Progenitor Genome Organization and Cellular Diversity", aims to investigate how the physical organization of the genome in neural progenitor cells impacts their ability to generate diverse neuronal subtypes during brain development. The research will leverage the Drosophila neuroblast system as an in vivo model to study the relationship between genome organization and cell-type specific gene expression programs. The project will run for approximately 5 years, with a scheduled completion date of July 31, 2030. This grant is funded under the NICHD's Child Health and Human Development Extramural Research program (CFDA 93.865), which supports a broad range of research on human development, reproductive health, and child/adolescent health issues.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $638.6k | 8/21/25 |