Project Grant R01HD118949
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to characterize the structural and functional brain development trajectories of offspring with and without prenatal exposure to maternal psychological distress (MPD). The $768,372 award, made on September 4, 2025, will support a longitudinal study to assess the neurodevelopmental...
- This $163,145 Project Grant awarded on August 7, 2025 by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research Program (CFDA 93.865), aims to address critical questions pertaining to impaired placentation associated with fetal growth restriction (FGR). The principal investigator, a pediatric and fetal surgeon, will use this 5-year award to develop unique cross-disciplinary skills and...
- This Project Grant award of $157,000.00, provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports a longitudinal, prospective study investigating the relationship between pregnancy stress, maternal mental health symptoms, sex steroid hormones, and postpartum maternal sensitivity. The study aims to determine the individual and coordinated trajectories...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $256,008 to Teachers College Columbia University to study the associations between maternal stress, infant epigenetics, and behavioral/cognitive development in early childhood. The research project aims to integrate epigenetic aging as a biomarker to explain the relationship...
- This federal Project Grant award for $378,123 from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research to identify and test mechanisms that establish transcriptional regulatory potency in early embryos. The primary activities include using genomic methods like PRO-seq, DREG, and OMNI-ATAC to characterize transcriptionally active regulatory elements, DNA accessibility, and...
- This $221,448 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to determine the role of apoptosis (programmed cell death) in oogenesis and oocyte (egg cell) health. The research will be conducted by the University of North Carolina at Chapel Hill using the oogenic germline of the model organism Caenorhabditis elegans. The goal is to...
- This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the CFDA program "Child Health and Human Development Extramural Research", provides $125,814 to support research on quantifying germ cell lineage dynamics in mammalian oogenesis (female egg cell development). The award aims to characterize the process of germ cell selection and the functional importance of early germ cell heterogeneity in shaping the developing ovarian...
- The federal Project Grant award of $429,000 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to characterize placental extracellular vesicles (EVs) throughout human pregnancy. The goal is to develop novel methods to image, count, isolate, and validate placental cell- and size-specific EVs from maternal blood, in order to monitor placental...
- This Project Grant award of $765,571 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research on placental fatty acid metabolism in gestational diabetes mellitus (GDM). The project aims to investigate sexual dimorphism in placental function and its role in adverse pregnancy outcomes associated with GDM, with a focus on understanding the effects of GDM...
- This federal Project Grant award, provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to understand the mechanism of pluripotency transitions during peri-implantation development. The $760,617 award to The Children's Hospital Corporation, doing business as Boston Children's Hospital, aims to address the technical challenges in working with limited...
This federal Project Grant award of $719,141, awarded on August 11, 2025 by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support a longitudinal study comparing maternal prenatal distress effects between in-vitro fertilization (IVF) donor oocyte/embryo and non-donor oocyte pregnancies. The study aims to rigorously test the developmental origins of health and disease (DOHAD) research model by leveraging IVF advancements to detect prenatal programming independent of shared maternal-child genes. Using multidisciplinary neurobehavioral, epigenetic, and transcriptomic methods, the study will enroll 180 pregnant individuals (60 donor oocyte/embryo, 120 non-donor oocyte) to examine the influence of maternal distress on perinatal neurobehavioral development, as well as its impact on placenta gene methylation. The primary awardee is The Trustees of Columbia University in the City of New York, conducting the research through its Health Sciences Division.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $719.1k | 8/11/25 |