Project Grant R01HD117068
- This $769,846 Project Grant was awarded on May 1, 2025 by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), under the Drug Use and Addiction Research Programs (CFDA 93.279). The funding supports the development of an innovative, girth-adjustable vaginal dilator device designed to significantly improve pain management for patients with chronic pelvic floor disorders. The technology aims to enable atraumatic vaginal...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $9,237,770 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to The Washington University to conduct the "IMPETUS: Integrated Mechanisms, Phenotypes, and Translational Underpinnings of Chronic Pain After Surgery" research project. The goal is to gain integrated mechanistic insights into peripheral and central biological processes that contribute to chronic postsurgical pain...
- This federal Project Grant award, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Drug Use and Addiction Research Programs (CFDA 93.279), is focused on developing novel methods for selectively stimulating nociceptors (pain receptors) and measuring the brain's nociceptive-specific response in both healthy individuals and those with the chronic pain condition fibromyalgia. The $2,314,276 award to Emory University will fund the creation of a new...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $1,516,765 to the University of California, Los Angeles (UCLA) to develop and validate an innovative near-infrared spectroscopy (NIRS) technology for the quantitative assessment of pelvic floor muscle function in patients with myofascial pelvic pain (MPP). The research aims to establish NIRS as an effective, non-invasive,...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $421,437 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the Regents of the University of Minnesota. The grant supports research to investigate sex differences in spinal dopaminergic mechanisms underlying neuropathic pain. The project aims to define the function of dopamine 1 receptors (DRD1) expressed in dorsal horn neurons and their role in nerve...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), awarded a $1,955,201 Cooperative Agreement to Cincinnati Children's Hospital Medical Center under the NIH Drug Use and Addiction Research Programs (CFDA 93.279). The 5-year award, effective September 19, 2025 through July 31, 2030, will support research to better understand the biopsychosocial determinants of pediatric-onset chronic musculoskeletal pain. The research will...
- This $764,659 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program supports research to investigate the mechanisms underlying neuropathic spontaneous pain. The key objectives are to characterize the role of local vascular movement in triggering neuropathic spontaneous pain, determine how mechanoreceptors in sensory neurons contribute...
- This is a $5,318,433 Project Grant awarded by the National Institute of Neurological Disorders and Stroke (part of the National Institutes of Health) under the Drug Use and Addiction Research Programs (CFDA 93.279). The grant will fund research to investigate the role of the gut microbiome in contributing to individual differences in lumbosacral radicular pain, including pain severity, impact, and persistence after treatment. The research will leverage machine learning techniques to accurately...
- This $4,039,366 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), will support a research project titled "A Fully Humanized Functional Genomic Screen to Identify and Validate Pain Therapeutic Targets" under the NIH's Drug Use and Addiction Research Programs (CFDA 93.279). The project will leverage innovative CRISPR-based screening and human dorsal root ganglion (DRG) transcriptomic data to...
- This federal Project Grant award in the amount of $5,057,591 was provided by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), under the Drug Use and Addiction Research Programs (CFDA 93.279). The purpose of the award is to conduct a comprehensive, prospective observational study with 2,400 emergency department patients seeking care for acute pain. The study aims to: 1) characterize clinically-informed pain phenotypes, 2)...
The National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), awarded a $4,867,750 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to The General Hospital Corporation (Massachusetts General Hospital) to conduct a 5-year study on "Understanding Vulvodynia: Using Machine-Learning-Based Modeling to Identify Factors Associated with Resolution and Persistence of Vulvar Pain." The study aims to prospectively collect data on multiple components of the vulvodynia pain experience and persistence of symptoms over 2 years in a cohort of 200 women ages 18-45 with vulvodynia. The research will involve standardized questionnaires, vaginal swabs for microbiome and inflammation analysis, quantitative sensory testing, and ecological momentary assessment via mobile device to identify factors associated with the resolution or persistence of vulvar pain.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $4.9m | 8/27/25 |