This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will support a $1,600,806 observational, longitudinal study to evaluate the effects of gender-affirming hormone therapy (GAHT) on brain development and executive function in 80 transgender and gender-nonbinary (TNB) adolescents. The study will use neuroimaging techniques to assess changes...
The National Institute of Child Health and Human Development (NICHD) awarded a $1,287,000 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the University of Colorado-Denver. The grant will fund a 2-year feasibility study to assess the processes and outcomes related to gender-affirming care for transgender and gender diverse youth in the United States. The study aims to (1) establish the acceptability of study instruments and data...
This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 - Child Health and Human Development Extramural Research, aims to evaluate the effect of exogenous anti-Müllerian hormone (AMH) on ovarian function and fertility in non-human primates. The $724,714 award will support research to test hypotheses that AMH can induce contraception without disrupting estradiol homeostasis, reduce ovarian aging, and potentially...
This Project Grant awarded by the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support research to investigate how the gut microbiome composition impacts gastrointestinal (GI) and central nervous system (CNS) function in a mouse model of autism spectrum disorder (ASD). The $430,375 award to the partnership between Henry Ford Health and Michigan State University Health Sciences will...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $1,559,542 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to The Medical College of Wisconsin, Inc. to study the cardiometabolic impacts of gender-affirming hormone therapy (GAHT) in transmasculine young adults. The project aims to determine the effects of GAHT on vascular endothelial function, cardiometabolic biomarkers, and sex hormone receptor expression in this population, compared to cisgender...
This is a Project Grant awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research Program (CFDA 93.855). The grant aims to explore the impact of gender-affirming hormone therapy on HIV viral dynamics and immune responses in transgender women. The $2,314,470 award will fund research over a 5-year period from November 2024 to October 2029. The principal investigator is leveraging two cohorts of transgender women, including a...
This Project Grant award of $654,475 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, will support research to characterize the impact of gender-affirming hormone therapy (GHT) on pain and pain-related symptoms in gender minority (GM) adults. The key objectives are to: 1) Characterize the trajectory of pain and pain-related symptoms in GM adults...
This $158,085 Project Grant, awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), will fund a mixed methods study to assess and promote vaginal health for transgender men on testosterone. The study aims to: 1) Develop a survey instrument to measure the vaginal health of transgender men on testosterone for clinical use; 2) Examine the psychometric properties of the survey items to finalize the...
This federal Project Grant award of $2,156,700 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will fund a mixed-methods study to prospectively examine multi-level impacts on family formation plans among sexual and gender minority (SGM) couples. The study aims to quantitatively test the influence of factors like state-level structural stigma and couple...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $412,500.00 in funding to the University of South Florida (USF) to conduct a longitudinal study of gut dysbiosis in anemic preterm infants. The goal is to determine the hematocrit threshold associated with gut microbiome changes and how anemia development influences the microbiome and host interactions...