Project Grant R01HD115645

Award Date 9/1/24
Completion Date 6/30/29
Dollars Obligated $708K
Federal Grant Program
93.865
Assistance Type
Project Grant
Place of Performance
Houston, TX 77030, USA
Similar Awards
This is a Project Grant awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) for the project titled "EARLY LIFE STRESS AND DIFFERENTIAL EFFECTS ON THE MOLECULAR MATURATION OF SPECIFIC SUBTYPES OF BRAIN SEROTONIN NEURONS". The $466,125 grant was awarded on August 25, 2023 to President And Fellows Of Harvard College, acting through the Harvard Medical School Division, to investigate the impact of early life stress and...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), will provide $633,671 to Rutgers, The State University of New Jersey to conduct research on the safety of prescription sleep medications in children, adolescents, and young adults with Attention Deficit Hyperactivity Disorder (ADHD). The key objectives of this 5-year research project are to: 1) evaluate nationwide patterns of prescription sleep medication...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) totaling $729,367 will study the impacts of a 2022 nationwide shortage of immediate-release formulations of amphetamine mixed salts (a class of prescription stimulant medications) on youth with Attention-Deficit Hyperactivity Disorder (ADHD). The research aims to: 1) measure the "amphetamine gap" and "stimulant gap" in communities and...
This is a Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The $1,857,842 grant will fund a 12-month randomized controlled trial to evaluate the efficacy of the drug romosozumab as an adjunct treatment to physiologic estrogen replacement in adolescents and young adults with functional hypothalamic amenorrhea. The research aims to determine if this combination...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $2,535,618 to The Children's Hospital Corporation (doing business as Boston Children's Hospital) to advance the understanding of genomic mechanisms underlying primary attention-deficit/hyperactivity disorder (ADHD) in families. The key objectives of this 5-year research project are to: 1) develop the largest family-based repository of...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to study the short- and long-term impacts of School-Based Health Centers (SBHCs) on student health care utilization, behavioral, educational, and economic outcomes. The $556,806 project, awarded to Northwestern University, will leverage over 13 years of prescription drug data and nearly a decade of...
This federal Project Grant award of $1,303,830 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research to measure and map trajectories of risk and resilience for suicidal thoughts and behaviors in sexual and gender minority (SGM) preteens. The key objectives are to: 1) develop consensus on best practices for safely, ethically, and effectively sampling, recruiting, and retaining SGM preteens at risk for suicide into...
This Project Grant award, with a total funding of $180,059, was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The award supports a study titled "Optimizing Developmental Outcomes in Early Childhood After Neonatal Opioid Withdrawal Syndrome" at the Research Institute at Nationwide Children's Hospital (RINCH), a prominent non-profit research organization. The key objectives of this study are to: 1) engage with...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $818,413 to Kaiser Foundation Hospitals to conduct research on improving antidepressant treatment selection. The key objectives are: 1) Rigorously testing assumptions about predicting antidepressant response, 2) Developing practical decision rules to guide antidepressant selection, and 3) Identifying valid treatment response phenotypes to...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $641,263 to The Johns Hopkins University to explore the use of epigenetic biomarkers as predictors of premenstrual dysphoric disorder (PMDD) and selective serotonin reuptake inhibitor (SSRI) treatment response. The primary objective is to assess whether epigenetic biomarkers previously identified as predictive of postpartum depression...

This federal Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) provides $707,858 to Baylor College of Medicine to study the long-term effects of selective serotonin reuptake inhibitor (SSRI) antidepressants on height growth suppression in adolescents.

The key objectives are to: 1) determine if the suppression of height growth and insulin-like growth factor 1 (IGF-1) continues over a 2-year follow-up period; 2) examine differences between the 4 most commonly prescribed SSRIs; and 3) assess whether SSRI treatment merely slows growth or stunts anticipated adult height. The study will involve serial bone age assessments to evaluate long-term growth impacts. Baylor College of Medicine has subcontracted $31,132 to The Children's Hospital of Philadelphia to provide expertise in measuring height and interpreting bone age data.

The findings from this 5-year research project are expected to provide critical insights into a potentially underrecognized side effect of a widely used medication class, informing clinical decision-making around SSRI prescriptions for adolescents.

Generated 6/10/25, 4:42 AM