Project Grant R01HD115636
- This $429,000 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) aims to determine if blood perfusion and microvascular pressure around the internal os of the uterine cervix can distinguish patients with a history of cervical insufficiency (CI) from normal controls in a non-pregnant state. The researchers at Thomas Jefferson University will use contrast-enhanced...
- This $184,880 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports the development of an innovative strategy to evaluate women presenting with non-specific symptoms of ectopic pregnancy. The project aims to leverage point-of-care ultrasound (POCUS) devices, novel ultrasound collection procedures, and deep learning artificial...
- This federal Project Grant award, funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), is supporting research on the role of decidual extracellular vesicles in mediating placental insufficiency. The $654,671 award, which commenced on August 1, 2025 and is scheduled for completion by April 30, 2030, is being conducted by the awardee, Yale University. The key...
- The National Institute of Child Health and Human Development (NICHD) has awarded a $423,985 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the University of Illinois to develop a novel non-invasive monitoring system for detecting placental dysfunction and associated pregnancy complications. The funding will support research to utilize extracellular vesicles (EVs) circulating in maternal blood as biomarkers, using a "target recycling...
- The National Institute of Child Health and Human Development (NICHD) awarded a $429,000 Project Grant (CFDA 93.865: Child Health and Human Development Extramural Research) to Thomas Jefferson University, doing business as Sidney Kimmel Medical College, to develop a new imaging tool to assess placental hemodynamics during pregnancy. The study aims to determine if Subharmonic Aided Pressure Estimation (SHAPE) using contrast-enhanced ultrasound can provide a safe, non-invasive, and real-time method...
- This $163,145 Project Grant awarded on August 7, 2025 by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research Program (CFDA 93.865), aims to address critical questions pertaining to impaired placentation associated with fetal growth restriction (FGR). The principal investigator, a pediatric and fetal surgeon, will use this 5-year award to develop unique cross-disciplinary skills and...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support the development of a new approach for secondary fetal screening using 0.55T MRI. The $707,218 project, running from June 1, 2025 to February 28, 2030, aims to assess the potential of 0.55T MRI to serve as a secondary fetal screening modality for high-risk pregnancies with...
- This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $442,550 to quantify altered placental microstructure and correlate microstructural changes with preeclampsia. The awardee, The Administrators of the Tulane Educational Fund (Tulane University), will develop quantitative ultrasound (QUS) methods to characterize the human placenta ex vivo and...
- This Project Grant award, funded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support research to develop non-invasive magnetic resonance imaging (MRI) techniques to predict fetal growth early in pregnancy. The $295,212 award, with a project period from September 1, 2024 to August 31, 2026, will be used by the University of South Australia to conduct a preclinical study in...
- The federal Project Grant award of $429,000 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to characterize placental extracellular vesicles (EVs) throughout human pregnancy. The goal is to develop novel methods to image, count, isolate, and validate placental cell- and size-specific EVs from maternal blood, in order to monitor placental...
This federal Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) provides $558,630 to the University of Wisconsin-Madison to elucidate the contribution of microvascular remodeling to cervical softening during pregnancy using quantitative ultrasound. The award, spanning from August 2025 to April 2030, aims to develop a novel microvascular ultrasound imaging method, named Statistical Microvascular Doppler (S-Doppler), to better understand the microstructural changes in the cervix that precede preterm delivery. The research leverages the university's expertise in statistical image reconstruction and deep learning to improve the resolution and sensitivity of ultrasound imaging, enabling in vivo detection of cervical microvascular changes during pregnancy. This work has the potential to lead to non-invasive methods for identifying cervical remodeling and improving the prediction and prevention of preterm birth.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $558.6k | 8/6/25 |