This federal Project Grant award of $160,000 from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) to Northwestern University supports research to directly evaluate the neural pathways involved in post-stroke hemiparesis. The objective is to generate fMRI data capturing activity in the corticospinal tract (CST) and cortico-reticulospinal tract (CRST) during unilateral hand-grasping tasks with the paretic versus...
The National Institute of Child Health and Human Development (NICHD) awarded a 5-year, $492,869 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to the Medical University of South Carolina (MUSC) to test the effects of a 12-week modified cardiac rehabilitation program on physical and psychosocial function in community-dwelling stroke survivors with and without post-stroke depression. The project, titled "Modified Cardiac Rehabilitation to Enhance...
The National Institute on Aging (NIA) awarded a $1,419,500 Project Grant (CFDA 93.866 - Aging Research) to the University of Southern California (USC) to understand the neural foundations of neuropsychiatric impairments, such as apathy, associated with Alzheimer's disease (AD) in mouse models. The 5-year project aims to explore cortical pathological, molecular, cellular, and transcriptional changes linked to the progression of neuropsychiatric symptoms in AD, as well as determine how cortical...
The University of Pittsburgh was awarded a $159,000 Project Grant by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant, awarded on May 7, 2025, with a final completion date of April 30, 2027, will fund a study to examine the feasibility of a randomized controlled trial comparing the effects of combining strategy training (ST) and acceptance and commitment therapy (ACT) versus ST...
The University of Utah received a $212,746 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) to characterize longitudinal post-acute rehabilitation (PAR) utilization and outcomes during the first year after stroke in Medicare beneficiaries. The project aims to: 1) identify subgroups of longitudinal PAR utilization patterns, 2) characterize PAR utilization subgroups by...
This federal Project Grant award from the National Institutes of Health (CFDA 93.865 - Child Health and Human Development Extramural Research) provides $675,676 to The Medical University of South Carolina to determine the efficacy of combining two known anti-depressant treatments, aerobic exercise and repetitive transcranial magnetic stimulation, on post-stroke depressive symptoms. The award will also examine whether successful reduction in depressive symptoms is associated with improved...
This $834,094 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to advance research on post-stroke cognitive impairment and dementia (PSCID). The funding will support a multi-year effort leveraging a national stroke registry and Medicare data to determine the incidence and prevalence of PSCID, identify associated risk factors, and explore potential pharmacological prevention strategies. Key aspects of the research include a patient-centered approach,...
This Project Grant award of $220,947.00, provided by the National Science Foundation's Engineering program (CFDA 47.041), supports fundamental research to develop an intelligent wearable system that can assess patient motivation, adapt the challenge level of therapeutic activities, and cue stroke survivors to engage in prescribed exercises. The goal is to address the problem of "learned non-use", where stroke survivors refrain from using their impaired limbs despite retaining the...
This federal Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under CFDA Program 93.865 Child Health and Human Development Extramural Research, provides $185,713 to the Rehabilitation Institute of Chicago (doing business as Shirley Ryan AbilityLab) to study neuromodulatory strategies targeting cortical and spinal pathways to facilitate paretic leg motor control during walking in individuals with stroke. The key objectives are...
This Federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) for $146,922 will support a study to evaluate the relationship between life-space and long-term cognitive decline after stroke. The key objectives are to: (1) estimate the effects of life-space components on cognitive decline following stroke in a large observational cohort, (2) characterize the life-space of stroke survivors using geolocation data, and (3) prospectively evaluate the effect of...