This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) totals $218,265 and will run from August 2024 to July 2026. The funding will support research to develop quantitative ultrasound imaging (QUS) techniques to detect cell death in the brains of human neonates, with a focus on infants who have experienced perinatal asphyxia. The project aims to first...
This Project Grant award of $260,887 from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) will fund research at The Children's Hospital of Philadelphia (CHOP) to study the effects of chronic in utero hypoxia on the placenta, brain, and epigenome. The research team will leverage expertise in neuroscience, imaging, pathology, and placental biology to conduct 4D in utero MRI studies (4D-UMRI) to examine the...
The National Institute of Child Health and Human Development (NICHD) awarded a $481,250 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to Oregon Health & Science University (OHSU). The grant, awarded on September 1, 2024, will support research to investigate the mechanisms of neuroinflammation and perinatal brain injury associated with intrauterine infection by the bacteria Ureaplasma parvum. Specifically, the project aims to assess...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $485,925 to the University of Massachusetts Boston to develop novel antioxidant compounds for treating preeclampsia, a life-threatening pregnancy complication. The primary goal is to design and synthesize cationic hydrazone antioxidants that can target mitochondria to reduce oxidative stress, improve...
This federal Project Grant award of $152,216 from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) to the University of Washington supports research to evaluate the association between adverse maternal factors in pregnancy and child neurodevelopmental outcomes in Kenya. The key objectives are to: 1) Determine how adverse maternal factors such as older age, depression, anemia, HIV infection, and nutritional...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), funds the development and validation of a machine learning-based fetal monitoring system to predict and prevent fetal hypoxia. The $261,310 award will support the creation of a high-sensitivity, high-specificity predictive model using a multi-site dataset of 50,000 fetal monitoring tracings coupled with...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $472,616 to Oregon Health & Science University (OHSU) to conduct research on mechanisms underlying memory impairment in preterm infants experiencing acute respiratory failure. The project aims to 1) determine if neonatal hypoxia disrupts hippocampal neuronal maturation...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $1,033,334 to support a research project titled "Nutrition, Late Fetal and Neonatal Mortality in the African Context." The goal of this 5-year project, effective September 16, 2024, is to improve understanding of the high levels and atypical age patterns of stillbirths and neonatal...
This Project Grant award, provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports a comparative study investigating the mechanistic effects of human milk feeding on neurodevelopment in preterm infants. The $239,399 award to the Regents of the University of Idaho will utilize a neonatal piglet model to examine how human milk feeding influences intestinal barrier function,...
This $779,911 Project Grant awarded by the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) aims to evaluate the impact of a music-based intervention (MBI) on preterm infant stress, brain development, and long-term neurodevelopmental outcomes. The MBI will be delivered to preterm infants in the neonatal intensive care unit (NICU) between 32-40 weeks gestation, with outcomes assessed during the NICU stay and up to 2...