Project Grant R01GM166835
- Federal Grant Award Summary Vanderbilt University received a $435,875 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective June 1, 2026 through January 31, 2031. This research initiative focuses on elucidating the structural mechanisms of calcium signaling at endoplasmic reticulum-mitochondria contact sites (EMCs), which are critical to mitochondrial function and cellular survival....
- Federal Project Grant Award Summary Award Details: Vanderbilt University received a $474,174 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2026, through April 30, 2031. The award supports research conducted at Vanderbilt's Nashville, Tennessee location through the university's Sponsored Programs Administration division. Research Objectives and Deliverables: The...
- Federal Grant Award Summary Vanderbilt University received a $342,570 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded June 1, 2026, with completion targeted for February 28, 2030. The award supports fundamental research into ubiquitin-mediated regulation of DNA double-strand break (DSB) repair pathway selection in budding yeast (Saccharomyces cerevisiae). The research investigates...
- Federal Grant Award Summary Vanderbilt University has been awarded $558,651 through the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) for a five-year Project Grant beginning August 1, 2025 and concluding July 31, 2030. The award supports research on the discovery and engineering of ribosomally synthesized and post-translationally modified peptides (RIPPs), with focus on advancing genomics, enzymology, and structure-function...
- Federal Grant Award Summary Vanderbilt University received a $1.2M project grant awarded September 1, 2025, from the National Science Foundation's Division of Computer and Network Systems under the Computer and Information Science and Engineering (CISE) program (CFDA 47.070). The project, titled "Intelligent Cyber Microscopy System for Long-Term Microscope Imaging" (ICMS), will develop an AI-powered cyber-physical system that transforms biological microscopy capabilities through the...
- Federal Project Grant Award Summary Vanderbilt University received a $4.0 million Project Grant award dated July 15, 2025, from the National Science Foundation's Office of Integrative Activities under the Integrative Activities program (CFDA 47.083). The award will support the development of a next-generation Matrix-Assisted Laser Desorption/Ionization (MALDI) Trapped Ion Mobility Fourier Transform Ion Cyclotron Resonance (FT-ICR) mass spectrometry platform for high-performance molecular...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded Stanford University a $616,000 Project Grant on March 12, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop next-generation proximity labeling (PL) enzymes for enhanced spatial proteomics research. The project, which extends through February 29, 2028, focuses on engineering and optimizing two innovative enzymes—FLEXID and LACCID—to improve the mapping of...
- Federal Grant Award Summary Vanderbilt University Medical Center received a $433,985 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded March 15, 2026, with completion targeted for December 31, 2030. The grant funds the development of advanced statistical and quantitative methodologies to support human microbiome research analytics. The research lab will address critical data analysis...
- Federal Grant Award Summary Duke University's Office of Research Administration has received a $482,750 Project Grant from the National Institute of General Medical Sciences under the Biomedical Research and Research Training program (CFDA 93.859), effective May 1, 2026 through February 28, 2031. This award funds the development of computational methods for in-situ structure determination using cryo-electron tomography (cryo-ET), specifically single-particle cryo-ET (SP-cryo-ET) workflows. The...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded Vanderbilt University $435,875 under the Biomedical Research and Research Training program (CFDA 93.859) to support investigator-initiated research on epigenetic control of tissue regeneration. The award, effective July 1, 2026, through April 30, 2031, funds fundamental research investigating how gene activity is regulated across diverse cell types during tissue regeneration in species such...
Vanderbilt University received a $1.74 million Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) for a four-year project period running from August 1, 2026 through July 31, 2030. The grant funds the development of genetically encoded dual-visible protein tags capable of simultaneous visualization by both light microscopy (LM) and electron microscopy (EM) to enable molecular-resolution three-dimensional cell imaging. This research addresses a critical gap in cellular imaging by creating universal protein tags with unambiguous identification at resolutions better than 2 nanometers while maintaining native cellular conditions. The project delivers two primary research products: (1) engineered and optimized electron microscopy-visible protein scaffolds with defined geometry that improve stability and detectability for in vitro applications, and (2) validated LM/EM dual-visible labeling methodologies for three-dimensional cell imaging at the molecular level. The research employs well-characterized biological systems and proof-of-concept experiments to bridge the existing resolution gap between light microscopy and cryo-electron tomography techniques, thereby advancing fundamental understanding of multi-protein assembly nanoscale organization and cellular mechanisms underlying disease.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.7m | 7/14/26 |