Project Grant R01GM164731
- This federal Project Grant award of $412,295 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports research on sequence transformations and computational biology at Carnegie Mellon University. The award period runs from September 1, 2025 to August 31, 2030. The research focuses on advancing the theory and software tools for approximate string matching in biological sequences, which is critical for...
- This federal Project Grant award of $532,276, awarded on July 14, 2025 by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), aims to expand the Open Case Study (OCS) Project and create Biomedical OCS (Bio-OCS). The Bio-OCS program will focus on building bioinformatics skills using cutting-edge methodologies and tools like AI and spatial transcriptomics, providing learners with a free archive of case studies to...
- This federal Project Grant award, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), aims to develop novel high-throughput machine learning approaches to study cell population-wide differences in subcellular object morphology, conformations, and organization using cryo-electron tomography (cryo-ET) data. The $371,427 award, granted on June 10, 2025, will support Carnegie Mellon University in addressing...
- This federal Project Grant award of $437,250.00 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), will fund a 5-year research project at the University of Pittsburgh focused on advanced computational approaches for integrating single-cell multi-omics data. The key objectives of this project are to: 1) Develop novel integration methods for combining single-cell RNA-seq, ATAC-seq, and cytometry data to...
- This federal Project Grant award of $245,753.00 by the National Science Foundation's Social, Behavioral, and Economic Sciences program (CFDA 47.075) supports research into the translation of scientific research, specifically human genomic analysis, into a medical tool for newborn genomic screening. The project investigates the scientific research, biotechnology actors, and other interested parties driving this development, as well as its effects on patients, healthcare systems, and society....
- The National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program awarded a $323,642 Project Grant to Carnegie Mellon University (CMU) on September 1, 2025. The grant supports a 5-year research project to develop new mathematical and computational models for understanding how the complex spatial structure of biological populations, such as cancer cells, microbial colonies, and human populations, influences their evolutionary dynamics. The project aims to create...
- This federal Project Grant award of $426,479 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), will support research toward developing statistical and computational tools to enable precision risk stratification, diagnosis, and treatment of medical conditions. The research will focus on integrating and synthesizing data from diverse sources such as biobanks, electronic health records, and clinical registries...
- This $244,450 Project Grant, awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to understand the catalytic mechanisms, structural dynamics, and biomedical importance of two key classes of metalloenzymes: matrix metalloproteinases (MMPs) and iron(II)/2-oxoglutarate (2OG)-dependent oxygenases. The project, spanning July 2025 to June 2030, aims to provide missing knowledge on these...
- This Project Grant awarded by the National Science Foundation (NSF) Division of Computing and Communication Foundations provides $499,995 to Carnegie Mellon University (CMU) for research on "Collaborative Research: DASS: Accountable Open Source Infrastructure." The project aims to investigate the extent to which open-source software maintainers are accountable to different user groups, and how this accountability emerges and varies over time. The research will use qualitative...
- This Project Grant award of $638,334 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) aims to advance the understanding of structural mechanisms underlying protein-small molecule binding and protein function. The project will develop novel computational methods for thermodynamic mapping of proteins, ligands, and surrounding aqueous solvent using molecular dynamics simulations. The goal is to create a...
This $241,506 federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports a research project titled "SOS: BIO: The Anatomy of Scientific Biomedical Open-Source Software--From Code to Communities" at Carnegie Mellon University. The key objectives of this 24-month project are to: (1) identify and characterize the biomedical open-source software (OSS) infrastructure through computational analysis of software origins, evolution, and usage patterns; (2) model the health and sustainability of biomedical OSS by examining maintenance practices, team dynamics, and abandonment risk factors; and (3) quantify the relationship between software maintenance status and scientific outcomes, including research productivity, reproducibility, and resource efficiency. The project employs a mixed-methods approach using data from the Chan Zuckerberg Initiative, World of Code, and OpenAlex to achieve these goals and advance understanding of the critical OSS infrastructure supporting modern biomedical research.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $241.5k | 9/5/25 |