Project Grant R01GM163164
- Federal Grant Award Summary Stony Brook University received a $432,569 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded on March 5, 2026, with a completion date of February 28, 2031. The research initiative, titled "Deciphering the Regulatory Mechanisms of Extracellular Particle-Mediated Signaling," focuses on elucidating how cells regulate the heterogeneous profiles of...
- Federal Grant Award Summary Stony Brook University received a $436,001 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective August 1, 2025 through July 31, 2027. The award supports development of an efficient and accessible spatial transcriptomics platform designed to deliver gene expression data at single-cell resolution within tissue spatial context. The project addresses current...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded $1,048,299 to The Research Foundation For The State University Of New York (RF-SUNY) on August 1, 2025, under the Biomedical Research and Research Training program (CFDA 93.859) to acquire a LUMICKS C-TRAP Correlative Force and Fluorescence Optical Tweezer System for the RNA Institute at the University at Albany. This instrument enables real-time observation, monitoring, and quantification of...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded $526,344 to Lawrence Berkeley National Laboratory under the Biomedical Research and Research Training program (CFDA 93.859) on July 21, 2025, for a project period extending through February 16, 2028. This Project Grant supports the development of advanced X-ray absorption spectroscopy (XAS) methods utilizing femtosecond pulses from X-ray free electron lasers (XFELs) to investigate chemical dynamics and...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded $436,361.00 under the Biomedical Research and Research Training program (CFDA 93.859) to support a five-year project (August 1, 2025 – July 31, 2030) focused on advancing protein structure determination methodologies. The Research Foundation for the State University of New York, serving as the fiscal agent for research conducted in Buffalo, will develop innovative computational algorithms and...
- Federal Project Grant Award Summary Arizona State University received a $1,977,264 Project Grant award, effective September 15, 2025, through August 31, 2029, under the National Institute of General Medical Sciences' Biomedical Research and Research Training program (CFDA 93.859). The award funds development of a novel multimodal imaging platform that integrates fluorescence super-resolution and tomographic polarized light imaging technologies to enable cellular and unicellular organism...
- Federal Grant Award Summary Boston University received a $1,926,960 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded September 15, 2025, with completion targeted for August 31, 2029. The grant funds development of robust, high-throughput superresolution (SR) imaging technology based on speckle illumination to address critical limitations in current fluorescence microscopy methods....
- Federal Grant Award Summary The University of Arizona received a $1.835 million Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded May 11, 2026, with completion targeted for April 30, 2030. The award funds the development of an innovative ultra-broadband microscope system based on an obscuration-free, off-axis freeform reflective optical architecture designed to overcome fundamental...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), awarded The Regents of the University of California, operating as Lawrence Berkeley National Laboratory, a Project Grant of $430,109 beginning June 1, 2026, with completion targeted for March 31, 2030. This award supports fundamental biomedical research focused on developing deeply subwavelength near infrared imaging technology using...
- Federal Project Grant Award Summary Molecular Instruments, Inc. received a $306,788 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) with an award date of September 30, 2025, and a completion date of September 29, 2026. The award supports the development and advancement of probe technology for ultrasensitive RNA imaging utilizing Hybridization Chain Reaction (HCR) methodology. The project...
The National Institute of General Medical Sciences (NIGMS) awarded Stony Brook University $1.37M under the Biomedical Research and Research Training program (CFDA 93.859) to develop a high-speed atomic force microscope-infrared (HS-AFM-IR) instrument. The four-year project, initiated June 1, 2026 and concluding May 31, 2030, will deliver an integrated imaging system combining atomic force microscopy with infrared spectroscopy to enable real-time, label-free visualization of biomacromolecule dynamics in aqueous environments. The instrument is designed to achieve approximately 5 nanometer spatial resolution with dual-composition chemical imaging capability, addressing critical limitations of existing microscopy technologies that either provide static images or require extrinsic labels. The HS-AFM-IR system will provide researchers with capability to observe biomolecular processes—including protein folding, enzyme catalysis, and drug-target binding—under physiologically relevant conditions in real-time. Key applications include tracking co-localization of multiple biomacromolecules, measuring antibody-antigen kinetics at the molecular level, and assessing how external factors such as pharmaceutical compounds, ions, and environmental conditions influence biomolecular conformations and interactions. This novel instrumentation represents a significant advancement over current microscopy tools for studying dynamic biomolecular systems inaccessible through conventional imaging approaches.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.4m | 5/22/26 |