Project Grant R01GM160992
- The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), awarded a $410,014 Project Grant to Trustees of Boston University to establish proof-of-concept for a new high-speed, real-time feedback-driven single particle tracking (RT-FD-SPT) fluorescence microscope with concurrent spectroscopic readout. The goal of this project is to develop an advanced tracking approach that leverages dual-stage scanners and nonlinear...
- This $307,754 National Science Foundation Engineering Directorate project grant will fund the acquisition of a Nikon CSU-W1-SORA super-resolution spinning disk confocal microscope for Boston University. The microscope will enable new spatially resolved transcriptomics and multi-scale connectomics research techniques to study gene expression within cells and neural connectivity in brain networks. As a shared resource housed in BU's Photonics Center, the microscope is expected to serve nine...
- This $1,977,264 federal Project Grant, awarded by the U.S. Department of Health and Human Services' National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), aims to develop a novel multimodal imaging platform that combines fluorescence super-resolution and tomographic polarized light imaging. The project will create open-source computational imaging tools to recover the dielectric tensor in multiple scattering samples using...
- This Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) provides $749,227 to the Trustees of Boston University for the acquisition of a three-photon microscopy system. The system will support fluorescence and phosphorescence lifetime imaging capabilities to enable researchers at the university's Neurophotonics Center to image intact brain tissue up to 1.2 mm in depth with sub-micron resolution. This state-of-the-art imaging...
- This Project Grant award of $727,297 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), will enable Colorado State University (CSU) to acquire a new 3i Marianas super-resolution spinning disk confocal microscope. This cutting-edge imaging system will enhance CSU's research capabilities across a broad range of biological models, including yeast, mammalian cell culture, organoids, tissue slices, and model...
- This Project Grant award, valued at $1,963,850.00 and awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports the development of a novel "Differentiable Microscopy" technology at the Massachusetts Institute of Technology (MIT). The project aims to create a high-throughput, end-to-end imaging cytometry system by leveraging customizable nano-optics and machine learning techniques. The goal...
- The National Institute of General Medical Sciences (NIGMS) awarded a Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the University of Maryland, College Park. The $526,451 grant, awarded on May 1, 2025, supports the development of a novel optical microscopy modality for cell biomechanics research based on pulsed stimulated Brillouin scattering (SBS). The goal is to create a non-contact, non-perturbative, and high-resolution system to study the...
- This federal Project Grant award of $349,280 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports the development of advanced machine learning algorithms for ultra-high-density, ultra-high-precision single molecule localization microscopy (SMLM). The grant recipient, Xgenomes Corp., will create a SMLM video simulator to generate training data (Aim 1), build a machine learning-based grouping...
- This $738,752 Project Grant was awarded on May 1, 2025 by the National Institutes of Health (NIH) Office of Research Infrastructure Programs (ORIP) under CFDA 93.351 for Research Infrastructure Programs. The funding will be used by the University of Colorado Boulder to acquire an Evident Scientific (Olympus) SPINSR super-resolution spinning disk confocal microscope for the university's Porter Biosciences Light Microscopy Core Facility. The new microscope will replace and update the...
- The U.S. Department of Health and Human Services, National Institute of General Medical Sciences (NIGMS) awarded a $449,625 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Trustees of Boston University. The grant, awarded on September 15, 2025, supports research to develop new experimental strategies and computational approaches for studying single-cell gene expression trajectories. The overarching goal is to enable foundational advances in...
This $1,926,960 Project Grant was awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to Trustees of Boston University on September 15, 2025. The grant aims to develop new algorithms, engineer speckle illumination, and integrate these technologies into microscopes that enable high-speed, multicolor, and volumetric (multiplane) superresolution imaging using standard fluorescent molecules. The goal is to create robust, high-throughput superresolution platforms for applications in spatial transcriptomics of mouse brain tissue, with the potential to achieve higher resolution and faster processing times compared to currently available superresolution technologies. This collaborative effort between optics and neurobiology labs seeks to establish the practical use of speckle-based superresolution imaging.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.9m | 9/8/25 |