Project Grant R01GM157692
Award Date 9/5/25
Completion Date 8/31/27
Dollars Obligated $795K
Funding Federal Agency
Awarding Federal Agency
Awardee
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Connecticut, USA
Similar Awards
- This federal Project Grant award of $460,740.00 was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to Yale University. The project aims to develop novel quantitative experimental and computational methods for studying continuous phenotypic transitions in cellular states, with applications across ovarian aging, cardiovascular disease, and hormone-dependent cancers. Key objectives include using...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $504,175.00 to Yale University to conduct research on the role of non-coding RNA in the regulation of pluripotent stem cell biology. The research program leverages the study of planarian stem cells to investigate how non-coding RNA, particularly PIWI-interacting RNAs (piRNAs), regulate processes like maintenance of...
- This federal Project Grant award of $669,801 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports research at Yale University to study the proteomic and phosphoproteomic remodeling associated with genomic imbalances, such as in aneuploid cells. The research aims to distinguish the mechanisms of proteomic remodeling and tolerance in chromosome gain versus loss type aneuploidies, as well as to apply...
- The Federal Grant Award of $669,737.00 was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to Yale University. The award, with a performance period from September 1, 2025 to August 31, 2027, supports a research project focused on investigating the principles underlying convective cell motion and its coordination with cell migration within tissues. The research aims to provide fundamental insights...
- This federal Project Grant award of $460,740 from the National Institute of General Medical Sciences (NIGMS) under CFDA 93.859 (Biomedical Research and Research Training program) will support research by Yale University to develop scalable methods for inferring the most important interactions within large biological networks. The goal is to investigate two model systems: (i) neural activity and (ii) chromatin structure, in order to identify the networks of interactions that best describe...
- This $224,088 federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports research at Harvard University to study the developmental origins of adult pluripotent stem cells. The project aims to identify the molecular and cellular mechanisms that govern the specification and maintenance of adult pluripotent stem cell populations in highly regenerative species. Specifically, the...
- This $361,283 Project Grant award, provided by the U.S. Department of Health and Human Services' National Institute of General Medical Sciences (NIGMS) under CFDA Program 93.859 Biomedical Research and Research Training, supports research at Yale University focused on advancing the fields of molecular structure analysis and molecular dynamics simulations. The research aims to develop novel methods and algorithms that leverage cutting-edge techniques like cryo-electron microscopy and molecular...
- The National Institute of General Medical Sciences (NIGMS) awarded a $222,708 Project Grant under CFDA 93.859 - Biomedical Research and Research Training to Yale University to develop peptide-containing transition metal catalysts for site-selective transformations of the antibiotic thiostrepton. This research seeks to enable selective modifications of complex natural product molecules, with the goal of potentially developing new and more potent antibiotics to address the growing challenge of...
- The federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) under CFDA program 93.859 - Biomedical Research and Research Training is supporting a $3,125,817 research project at New York University School of Medicine titled "Decoding Positional Epigenetic Memory." The project aims to decipher how stable positional identity is generated through the regulation of HOX gene expression, which is crucial for proper cell differentiation and disease...
- This $431,750 Project Grant awarded by the National Institute of General Medical Sciences (NIGMS) under CFDA 93.859 Biomedical Research and Research Training will support research at Cornell University to enhance the understanding of intercellular communication and its role in coordinating successful tissue regeneration. The project aims to (1) map the cellular and developmental trajectories that lead to different regenerative outcomes, (2) explore the role of intercellular signaling in...
The federal Project Grant award of $795,230.00 from the National Institute of General Medical Sciences (NIGMS), under CFDA 93.859 Biomedical Research and Research Training program, supports research at Yale University to develop chemical regulators of the YEATS4 protein to engineer cell fate plasticity. The goal is to enable more efficient conversion of somatic cells into induced pluripotent stem cells (iPSCs) using the transcription factors OCT4, SOX2, KLF4 and CMYC (OSKM). The research aims to provide a deeper understanding of cell fate plasticity, which could lead to the development of more efficient regeneration and rejuvenation therapies. The award period runs from September 5, 2025, to August 31, 2027.
Generated 10/21/25, 6:25 AM
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $795.2k | 9/3/25 |