Project Grant R35GM160552
- This federal Project Grant award, valued at $428,202.00 and funded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports a research project to elucidate the systems-level mechanisms that generate robustness in organ size and shape. The principal investigator, based at Cornell University, will leverage advanced live imaging, genetic engineering, image processing, and computational modeling to investigate...
- This $428,600 federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports an investigation into how RNA-directed feedback loops coordinate wound healing and regeneration. The research project aims to understand the conserved developmental pathways and heterochronic genes that regulate cell migration, fate, and timing during normal adult wound repair and regeneration,...
- This $223,176 federal Project Grant award from the National Institute of General Medical Sciences (CFDA 93.859 - Biomedical Research and Research Training) supports research at Weill Medical College of Cornell University investigating the role of signaling feedback in directed cell migration. The project aims to dissect the mechanisms by which cells regulate key signaling pathways, such as PI3K, RAS, and RAC, to control navigation during cell migration. The research will focus on understanding...
- This $1,737,000 Project Grant awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports the development of innovative single-cell genomics technologies for joint analysis of regulatory dynamics and transcriptional states. Key objectives include: Developing multiomics tools to measure rates of epigenomic changes (DNA methylation, demethylation, oxidative damage, DNA repair) and relate these to...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $627,797 to Cornell University to conduct research on the molecular mechanisms connecting endocytic and junctional complexes with epithelial pathology in the C. elegans model organism. The goal of this 5-year research program is to delineate the inner workings of membrane-associated protein complexes required for...
- This $423,890 Project Grant was awarded on September 1, 2025 by the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859). The grant is being used to support fundamental scientific research and advanced training focused on understanding the mechanisms underlying the survival and uncontrolled proliferation of stem cells with DNA damage, and the influence of surrounding tissues on stem cell behavior during tissue...
- This $381,801 project grant award from the National Institute of General Medical Sciences (CFDA 93.859 Biomedical Research and Research Training) will fund research at the University of California, Santa Cruz to gain insights into how biological timers control development and how the apical extracellular matrix is constructed and remodeled in the nematode model organism C. elegans. The research aims to understand the properties, components, and regulation of developmental timers that synchronize...
- This Project Grant award for $509,982.00 was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The award supports research conducted by the University of Maryland, College Park to unravel the fundamental mechanisms governing cell-cell communication and signal exchange during animal development. The research aims to characterize a novel "direct delivery" mechanism of extracellular signal...
- This $406,250 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports two primary research directions at the University of Pennsylvania. The first research direction focuses on understanding how transcription factor families coordinate complex developmental pathways to generate diverse cellular morphologies and cell types, with a focus on identifying new mechanisms of transcription...
- This federal Project Grant award in the amount of $311,770.00 was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The award is supporting research at Vanderbilt University to investigate the mechanisms of tissue repair, with a focus on understanding epithelial repair and basement membrane repair. The research aims to advance knowledge of how cells coordinate migration, proliferation, and...
This $431,750 Project Grant awarded by the National Institute of General Medical Sciences (NIGMS) under CFDA 93.859 Biomedical Research and Research Training will support research at Cornell University to enhance the understanding of intercellular communication and its role in coordinating successful tissue regeneration. The project aims to (1) map the cellular and developmental trajectories that lead to different regenerative outcomes, (2) explore the role of intercellular signaling in shaping these regenerative paths, and (3) test the potential for programmable regenerative engineering to produce predictable regenerative outcomes and mitigate tissue rejection. The award period runs from Sep 1, 2025 to Jul 31, 2030, with the goal of advancing foundational knowledge in regenerative biology to enable new regenerative medicine technologies.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $431.8k | 8/27/25 |