The National Eye Institute (NEI) of the National Institutes of Health awarded a $366,399 Project Grant (CFDA 93.867 - Vision Research) to the Trustees of Indiana University, doing business as Indiana University, to support research on the role of the PAX6 transcription factors in specifying and patterning the Drosophila compound eye. This 5-year project aims to fill critical gaps in understanding how the PAX6 genes Eyeless (ey) and Twin of Eyeless (toy) individually and collectively contribute to eye formation and development in the fruit fly model system. The research will leverage advanced molecular and genetic techniques to provide new insights into the fundamental processes underlying organogenesis, with potential implications for understanding human eye disorders such as aniridia caused by PAX6 mutations.
Generated 3/4/25, 6:21 AM