Project Grant R01EY036114

Award Date 7/1/24
Completion Date 4/30/28
Dollars Obligated $530K
Federal Grant Program
93.867
Assistance Type
Project Grant
Place of Performance
Augusta, GA 30912, USA

The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded a $530,013 project grant to the Augusta University Research Institute, Inc. (dba Georgia Health Sciences) to analyze sex- and race-specific differences in tear microRNAs (miRNAs) and proteins and their relationship to dry eye disease (DED) severity and subtypes. The 4-year project, starting on July 1, 2024, aims to discover reliable DED biomarkers that can improve diagnosis and enable personalized treatment. It will also create a comprehensive reference database of miRNAs and proteins detected in human tear fluid. Additionally, the project involves a sub-award to the University of Texas Southwestern Medical Center to serve as a clinic site for patient recruitment and sample collection. The research seeks to advance understanding of the molecular mechanisms underlying DED and guide the development of targeted therapeutic interventions.

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