This Project Grant award from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) provides $510,689 to Georgia TECH Research Corp, a non-profit research institution, to conduct a 5-year research study on the functional organization and spatial resolution of attentional feedback from frontal to visual cortex.
The study aims to define the neural mechanisms underlying how cognitive control in the brain's frontal regions modulates sensory processing and perceptual intensity in the visual cortex. Using advanced techniques like functionally-targeted multi-area recordings and optogenetics in mice, the research will investigate the retinotopic precision and functional organization of top-down feedback projections from the anterior cingulate cortex to primary and higher-order visual areas. This work is expected to establish a detailed blueprint for how cognitive states like attention influence sensory perception, providing greater understanding of cognitive flexibility and insight into conditions characterized by attentional or perceptual deficits.
Generated 3/18/25, 4:33 AM