This federal Project Grant award from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) provides $638,267 to The Schepens Eye Research Institute, Inc. to investigate optic neuropathy in familial dysautonomia. The research aims to develop retina-specific treatments to rescue visual function, including evaluating the efficacy of systemic and local therapeutic approaches. Additionally, the project will seek to understand the molecular mechanisms behind selective retinal ganglion cell loss in this condition. The research will leverage mouse models and patient-derived induced pluripotent stem cell retinal ganglion cells to directly translate findings into the best treatment strategies. The award commenced on April 1, 2025 and is slated for completion by March 31, 2030.
Generated 3/25/25, 5:42 AM