Project Grant R01ES038233
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) Environmental Health program (CFDA 93.113) awarded $249,000 to the University of North Carolina at Chapel Hill on August 13, 2025, for a research project extending through July 31, 2028. This Project Grant supports longitudinal research characterizing the early life chemical exposome and its impact on structural and functional brain development in children from birth through age five. The research...
- Federal Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded a $157,500 Project Grant to the Regents of the University of California at Riverside on July 9, 2025, under the Environmental Health program (CFDA 93.113). This two-year award (completion date: July 8, 2027) funds pilot research investigating gene-environment interactions in autism spectrum disorder (ASD) risk through developmental exposure to per- and polyfluoroalkyl substances (PFAS), commonly...
- Federal Grant Award Summary Drexel University received a $111,199 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), effective April 3, 2026 through March 31, 2028. The research project investigates the role of phthalates and phenols—endocrine-disrupting chemicals (EDCs) with widespread presence in dietary and personal care products—on phenotypic variability in autism and co-occurring neurodevelopmental...
- Federal Grant Award Summary Duke University's Office of Research Administration received a $444,125 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113) on February 17, 2026, with completion targeted for February 16, 2028. The award supports the development and validation of machine learning (ML) models to identify endocrine-disrupting plastic additives posing public health risks. The project deliverables include:...
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $1,006,211 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded February 17, 2026, with completion targeted for January 31, 2034. The grant supports research to elucidate how environmental chemical exposures affect mitochondrial function and interact with genetic mitochondrial disease conditions. The...
- Federal Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded the University of North Carolina at Chapel Hill a $249,000 Project Grant under the Environmental Health program (CFDA 93.113) on September 12, 2025, for a three-year research initiative examining "Phthalates and Phthalate Alternatives and Early Human Cardiometabolic Development." The award supports investigation of associations between prenatal exposure to phthalates and phthalate...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded the University of Pennsylvania a $124,728 Project Grant on September 8, 2025, under the Environmental Health program (CFDA 93.113) to conduct research on gestational and childhood exposure to endocrine-disrupting chemicals (EDCs) and their effects on adolescent neurobehavior. The research will deliver scientific investigation into the mechanisms by which EDCs—including polybrominated...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded The Pennsylvania State University a $249,000 Project Grant on August 12, 2025, under the Environmental Health program (CFDA 93.113) to conduct research examining the interaction between perinatal organophosphate flame retardant (OPFR) exposure and adult chronic stress on cognitive processing. The project, extending through July 31, 2028, will investigate how early developmental exposure to...
- Federal Project Grant Award Summary Boston University Medical Campus received a $147,486 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded November 1, 2025, with completion targeted for August 31, 2028. This research project will investigate the neurodevelopmental impacts of early-life exposure to ferroalloy metal mixtures—including manganese, lead, chromium, and copper—on adolescent cognitive...
- Federal Project Grant Award Summary North Carolina State University received a $418,000 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025 through July 31, 2027. This exploratory research project investigates the causal relationships between cockroach infestations and indoor environmental biocontaminants in low-income households. The research will elucidate how...
North Carolina State University received a $361,849 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), effective June 1, 2026, through March 31, 2031. The award funds research to investigate mast cells as a mechanistic link between developmental exposure to environmental toxicants—specifically the flame retardant Firemaster 550 (FM550)—and increased risk for neurodevelopmental disorders including Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD). The research will determine how developmental FM550 exposure induces persistent mast cell hyperactivity in both peripheral tissues and the brain, and how this hyperactivity amplifies inflammatory responses and behavioral deficits in a sex-specific manner. The project deliverables include three interconnected research aims examining the distinct contributions of peripheral versus brain mast cells to systemic and behavioral outcomes resulting from developmental FM550 exposure, assessing tissue-specific mast cell hyperactivity patterns, and identifying the mechanisms by which mast cell reprogramming increases susceptibility to systemic inflammation and neurodevelopmental disorders. By advancing mechanistic understanding of environmental chemical effects on neuroimmune development, this research directly supports NIEHS's mission to translate environmental health knowledge into strategies for reducing disease burden and promoting health, with particular relevance to vulnerable populations experiencing early-life environmental exposures.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $361.8k | 5/27/26 |