Project Grant R01ES036571

Award Date 6/6/25
Completion Date 3/31/30
Dollars Obligated $795K
Federal Grant Program
93.113
Assistance Type
Project Grant
Place of Performance
La Jolla, CA 92093, USA
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The National Institute of Environmental Health Sciences (NIEHS) awarded a $776,150.33 Project Grant under the Environmental Health (CFDA 93.113) program to the University of Massachusetts (UMass). The grant, titled "Triclosan, Pubertal Hormones, and the Gut Microbiome: Implications for Neurobehavior," will fund research examining the relationships between exposure to the antimicrobial compound triclosan, pubertal hormones, the adolescent gut microbiome, and neurobehavioral development....
This $478,503 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113) supports research to investigate the impact of prenatal exposure to per- and polyfluoroalkyl substances (PFAS) on the development of non-alcoholic fatty liver disease (NAFLD) in children. The award will leverage the existing GUSTO mother-child cohort in Singapore to conduct comprehensive assessments, including proton magnetic resonance...
The University of California, San Diego (UCSD) was awarded a $159,200 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) federal grant program. The project aims to characterize redox signaling during normal forebrain neurodevelopment in mice and examine the sensitivity of neuron subclasses to oxidative stress induced by environmental exposures like the herbicide paraquat and acetaminophen metabolites. Using a...
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The National Institutes of Health National Institute of Environmental Health Sciences awarded a $924,612 Project Grant to the California State University, East Bay Foundation, Inc. under the Environmental Health (CFDA 93.113) federal grant program. The grant will fund research from August 2022 to July 2025 to advance chemical risk assessment and predictive toxicology through the development, validation and integration of high-throughput mechanistic in vitro assays. Specifically, the grantee will...
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This $794,841 federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program supports research at the University of California, San Diego (UCSD) investigating the effects of early-life exposure to the antimicrobial chemical triclosan through breastfeeding on the development of fatty liver disease in adulthood. The research aims to elucidate the mechanisms by which lactational triclosan exposure heightens the risk and severity of liver disease in individuals consuming high-fat, high-fructose diets, with a focus on examining the roles of endoplasmic reticulum stress, intestinal barrier disruption, and epigenetic changes. The project will leverage expertise from UCSD researchers to provide novel insights into how early-life environmental toxicant exposures can predispose individuals to metabolic dysfunction-associated steatotic liver disease later in life.

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