Project Grant R01EB039036
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of North Carolina at Chapel Hill $570,612 on April 7, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop advanced volumetric ultrasound systems for functional imaging and multi-targeted closed-loop neuromodulation. The project addresses current limitations in ultrasonic neuromodulation by moving beyond MRI-dependent targeting...
- The National Institute of Biomedical Imaging and Bioengineering awarded Weill Medical College of Cornell University $678,471 on June 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a compact, portable transcranial Doppler ultrasound device for automated embolus detection in at-risk stroke patients. The funded work addresses the clinical gap in long-term, automated embolus monitoring outside clinical...
- The National Institute of Biomedical Imaging and Bioengineering awarded The Leland Stanford Junior University $2,421,019 on August 5, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to optimize milli-spinner thrombectomy technology for acute ischemic stroke treatment. The funded work addresses the failure of current thrombectomy devices (aspiration and stent-retrievers) in approximately 15 percent of acute ischemic stroke...
- The National Institute of Biomedical Imaging and Bioengineering awarded Virginia Polytechnic Institute & State University $563,970 on August 19, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop an ultrasound-guided handheld histotripsy system for precise and tissue-selective thyroid ablation. The project targets thyroid tumors using histotripsy, a non-thermal ultrasonic therapy method that ablates tissue...
- The National Institute of Biomedical Imaging and Bioengineering awarded Georgia TECH Research Corp $603,818 on April 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop and demonstrate a combined intravascular ultrasound (IVUS) and fractional flow reserve (FFR) microcatheter for guiding complex percutaneous coronary interventions. The project delivers a 2.5F coronary microcatheter integrating an FFR sensor...
- The National Institute of Biomedical Imaging and Bioengineering awarded Vanderbilt University $542,947 on March 3, 2026, to develop fully non-invasive transcranial functional ultrasound imaging for adult humans under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The project applies signal processing and machine learning techniques to enhance low-velocity blood flow imaging through the skull, translating functional ultrasound...
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $366,006 Project Grant (CFDA 93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health) to the Georgia Tech Research Corporation to develop flexible piezo film intravascular ultrasound (IVUS) arrays on guidewires and catheters. The goal is to integrate IVUS imaging capability onto standard guidewires and catheters used in over 1 million percutaneous coronary and peripheral...
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $365,523 Project Grant (CFDA 93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health) to the Georgia Tech Research Corporation to conduct research on using ultrasound imaging to track macrophage trafficking in tissue. The key objectives are to: Determine the detection limit of macrophages labeled with ultrasound contrast agents (microbubbles) under different ultrasound...
- The National Institute of Neurological Disorders and Stroke awarded Emory University $430,375 on June 22, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop x-ray dark-field imaging technology for carotid hemodynamic analysis using anisotropic iron oxide nanorods as contrast agents. The research addresses cerebrovascular disease assessment and plaque vulnerability prediction by advancing grating-based interferometric...
- The National Institute of Neurological Disorders and Stroke awarded The Leland Stanford Junior University $154,274 on May 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop small-focus transparent transducers for transcranial ultrasound stimulation in mice. The research addresses the absence of noninvasive tools for focal brain-wide neuromodulation, a limitation that constrains circuit-based understanding of neural...
The National Institute of Biomedical Imaging and Bioengineering awarded Georgia TECH Research Corp $625,554 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a robotically-delivered therapeutic ultrasound system for safe, effective treatment of large vessel occlusive stroke. The project addresses the clinical challenge that 75 percent of large vessel occlusive stroke patients fail on first-attempt endovascular mechanical thrombectomy, requiring multiple passes that reduce favorable clinical outcomes to 35 percent compared to 75 percent for single-pass success. The recipient will develop a 2 millimeter ultrasound delivery device to enable rapid clot dissolution in the internal carotid artery terminus and proximal middle cerebral artery, improving on previous 3 millimeter devices. Work includes validation testing using patient-specific, 3D-printed phantoms derived from de-identified computed tomography scans and testing in an animal model. The project addresses three specific aims: rapid ultrasound therapy and monitoring with stentriever-based imaging to guide treatment; effective delivery of ultrasound and aspiration through a modular system; and assessment of ultrasound and delivery conditions to prevent injury to surrounding tissue. Performance occurs in Georgia through May 31, 2030. The assistance type is Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 9/3/26 | ||
| Not listed | $625.6k | 8/28/26 |