Project Grant R01EB038261
- The National Institute of Biomedical Imaging and Bioengineering awarded Virginia Polytechnic Institute & State University $750,993 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop accurate, robust, and practical pulse-echo speed-of-sound imaging methods for clinical ultrasound applications. The project combines physics-based inversion and deep learning approaches to enable two-dimensional,...
- Federal Project Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $428,578 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The award, effective September 1, 2025 through August 31, 2027, supports research into focused ultrasound (FUS) therapies for non-invasive treatment of...
- The National Institute of Biomedical Imaging and Bioengineering awarded Georgia TECH Research Corp $625,554 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a robotically-delivered therapeutic ultrasound system for safe, effective treatment of large vessel occlusive stroke. The project addresses the clinical challenge that 75 percent of large vessel occlusive stroke patients fail on first-attempt...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of North Carolina at Chapel Hill $570,612 on April 7, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop advanced volumetric ultrasound systems for functional imaging and multi-targeted closed-loop neuromodulation. The project addresses current limitations in ultrasonic neuromodulation by moving beyond MRI-dependent targeting...
- The National Institute of Biomedical Imaging and Bioengineering awarded Iowa State University of Science and Technology $215,723 on August 14, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a next-generation, handheld, battery-powered, wireless dual-mode ultrasound-photoacoustic imaging system integrating high-power nanosecond pulsed light-emitting diodes. The project addresses a gap in current imaging...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of Virginia $190,847 on June 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop force-based metrics and haptic feedback technology for robotic paraesophageal hernia repair. The research will establish objective performance indicators for complex surgical procedures by integrating force-sensing technology and haptic feedback...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of Texas at Arlington $378,411 on April 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop super-resolution tomographic imaging technology for deep tissue visualization. The project aims to overcome diffraction limits inherent in existing super-resolution imaging modalities—including super-resolution fluorescence...
- The National Institute of Biomedical Imaging and Bioengineering awarded George Mason University $265,018 on August 15, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a disposable wearable ultrasound patch for real-time, noninvasive monitoring of cardiac output and blood pressure in neonates and infants following cardiac surgery. The project addresses the absence of continuous hemodynamic monitoring solutions...
- The National Cancer Institute awarded the University of Virginia $404,349 under the Cancer Detection and Diagnosis Research program (CFDA 93.394) on April 1, 2026, to develop and validate quantitative magnetic resonance imaging methods for measuring macromolecular delivery to brain tumors following focused ultrasound and microbubble treatment. The research addresses the blood-tumor barrier, which limits therapeutic drug delivery to brain metastases and contributes to higher patient mortality...
- The National Institute of Biomedical Imaging and Bioengineering awarded a Cooperative Agreement totaling $817,865 to Massachusetts General Hospital on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The award funds development of Acoustic Diffraction-Resistant Adaptive Profile Technology (ADAPT) to improve shear wave elastography, a non-invasive ultrasound technology for liver fibrosis staging and breast...
The National Institute of Biomedical Imaging and Bioengineering awarded Virginia Polytechnic Institute & State University $563,970 on August 19, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop an ultrasound-guided handheld histotripsy system for precise and tissue-selective thyroid ablation. The project targets thyroid tumors using histotripsy, a non-thermal ultrasonic therapy method that ablates tissue through acoustic cavitation control while preserving critical structures such as blood vessels, nerves, and the carotid artery. The approach combines miniaturized histotripsy transducer arrays operating at 1–4 megahertz with co-registered high-resolution imaging at 10–30 megahertz to enable ultrasound-guided ablation with increased imaging resolution and targeting precision. The flat array design permits simple skin coupling using ultrasound gel, addressing the anatomical complexity of thyroid surgery, which risks laryngeal paralysis, airway compromise, hemorrhage, and parathyroid gland injury. Performance occurs in Blacksburg, Virginia. The period of performance runs from August 19, 2026, through May 31, 2030. The assistance type is a Project Grant, which supports hypothesis-driven research related to discovery, design, development, and validation of technologies for biomedical imaging and bioengineering.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $564.0k | 8/18/26 |