Project Grant R01EB039025
- Federal Grant Award Summary Duke University received a $722,392 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), effective March 10, 2026, with completion targeted for February 28, 2030. The award supports the development and validation of four-dimensional smart epidermal photoacoustic tomography (4D-SEPAT) technology, a novel...
- Federal Project Grant Award Summary The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded the University of Pennsylvania a $616,897 Project Grant on August 8, 2025, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The award, with a completion date of July 31, 2026, funds development of synthetic intracellular microcompartments designed to enhance immune cell function in immunotherapy applications....
- Federal Grant Award Summary Duke University's Office of Research Administration received a Project Grant award of $127,527 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective November 1, 2025, with a completion date of April 30, 2028. The award supports investigator-initiated biomedical research focused on defining the role of the RGS12 locus in macrophage function, specifically examining how...
- Federal Grant Award Summary Duke University received a $3.19M Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded August 21, 2025, with a completion date of July 31, 2029. The grant supports research addressing immunomodulation in adeno-associated virus (AAV) gene therapy, a critical challenge in the treatment of monogenic disorders. AAV-based gene therapies are advancing clinically...
- Federal Grant Award Summary Duke University's Office of Research Administration received a $446,410 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective April 1, 2026 through March 31, 2030. The award supports the development and validation of advanced statistical methodologies designed to identify disease subtypes, with specific application to sepsis research. The project delivers three...
- Federal Project Grant Award Summary Duke University's Office of Research Administration was awarded $610,124 on February 4, 2026, under the National Institute of Allergy and Infectious Diseases (NIAID) Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct research on BCG-mediated immunotherapy against recurrent bladder infections. The project, which extends through January 31, 2031, will deliver scientific research and development services focused on developing an...
- Federal Grant Award Summary Duke University's Office of Research Administration received a $487,652 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), effective September 1, 2025, through August 31, 2030. The award funds research to elucidate the effects of blood and blood-derived components on meniscus tissue homeostasis, repair, and post-traumatic...
- Federal Grant Award Summary Duquesne University received a $231,131 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective June 11, 2025, with an ultimate completion date of May 31, 2027. The research focuses on developing injectable three-dimensional (3D) clustered fibroblastic reticular cells (FRCs) as a therapeutic approach to expand regulatory T cells (Tregs) and promote...
- Federal Project Grant Summary Duke University received a $3.18 million Project Grant award dated August 19, 2025, from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop an innovative bioprinted ventilated lung alveolar platform for investigating microbial interactions and influenza response. The project, which runs through July 31, 2029, aims to advance understanding of how the lung microbiome...
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $161,500 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded April 1, 2026, with a completion date of March 31, 2028. The grant funds the development of new genetic tools—specifically Cre (Cre/CreERT2) mouse models—designed to enable selective targeting and lineage tracing of plasma...
Duke University's Office of Research Administration received a $586,406 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), effective May 1, 2026, through February 28, 2030. The award funds research and development of Immunomodulatory Self-Assembled Peptides (ISAP), a supramolecular biomaterial technology platform designed to engage natural autoantibodies (NAAbs) as a therapeutic approach for treating chronic inflammatory diseases including inflammatory bowel disease, rheumatoid arthritis, psoriasis, atherosclerosis, and lupus. The research addresses significant gaps in current inflammatory disease treatment by developing a broadly applicable alternative to existing cytokine-blocking biologics, which suffer from variable efficacy, anti-drug antibody formation, and treatment failure in large patient populations. The ISAP technology aims to deliver long-lasting immunomodulation through engagement of multifactorial repair pathways central to chronic and acute inflammation, potentially reducing treatment unpredictability, monitoring burdens, and healthcare system costs associated with current standard-of-care approaches. Research will be conducted at Duke University's Durham, North Carolina facility, leveraging the institution's established biomedical research infrastructure and expertise in bioengineering and immunological research.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $586.4k | 4/21/26 |