Project Grant R01EB037561
- The National Institute of Biomedical Imaging and Bioengineering awarded $161,000 to the University of California, Davis on May 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop an affordable dynamic total-body positron emission tomography (TB PET) imaging system using sparse detector architectures. The research addresses cost barriers to TB PET adoption by reducing scintillator material and readout electronics...
- The National Institute of Biomedical Imaging and Bioengineering awarded $2.238 million to the University of California, Davis on May 12, 2026 under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop and evaluate whole-body parametric imaging methods for pediatric positron emission tomography (PET) imaging. The project develops a relative Patlak plot technique enabling quantitative kinetic imaging in pediatric cancer...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of California, Davis $701,020 on August 10, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop positronium lifetime tomography as a quantitative imaging modality for mapping tissue microenvironment in vivo. The project advances positronium lifetime tomography (PLT) as a novel diagnostic imaging technique complementary to...
- The National Institute of Biomedical Imaging and Bioengineering awarded The Regents of the University of California, operating Lawrence Berkeley National Laboratory, $312,165 on June 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop Time-of-Flight Multi-Photon Emission Tomography (TOF-MPET) for direct imaging of therapeutic radionuclides in cancer treatment. The project addresses limitations in current imaging...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of Southern California $663,498 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a modular microscale platform for rapid 18F-radiopharmaceutical production via click chemistry and droplet radiochemistry. The project addresses barriers in positron emission tomography tracer development by creating a...
- The National Institute of Biomedical Imaging and Bioengineering awarded The General Hospital Corporation (Massachusetts General Hospital) $100,000 on September 1, 2026, under the Trans-NIH Research Support program (CFDA 93.310) to develop a quantum-inspired computational framework for advanced positron emission tomography (PET) imaging. The project addresses clinical gaps in PET's ability to detect small lesions, distinguish subtle treatment effects, and reduce radiation dose. The framework...
- The National Institute of Biomedical Imaging and Bioengineering awarded The Johns Hopkins University $507,987 on April 23, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop scintillator-based photon counting detectors for X-ray computed tomography systems. The research addresses cost and image quality barriers in photon counting detector CT technology by replacing semiconductor-based detectors with...
- The National Institute of Biomedical Imaging and Bioengineering awarded Yale University $663,862 under Project Grant R01EB037707 on May 15, 2026, to optimize performance of the NeuroExplorer (NX), an ultra-high performance brain positron emission tomography system, and expand its capabilities for dynamic PET imaging with tracer kinetic modeling. The funded work addresses three specific aims. Aim 1 optimizes key aspects of system performance and reconstruction methodology to maximize image...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of Texas at Austin $618,695 on April 20, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop an adaptive and reconfigurable robot-assisted Single Photon Emission Computed Tomography (SPECT) imaging system. The project focuses on designing, integrating, and validating subsystems for a novel SPECT platform that personalizes imaging...
- The National Cancer Institute awarded The Trustees of The University of Pennsylvania $672,995 on August 1, 2026, under the Cancer Detection and Diagnosis Research program (CFDA 93.394) to develop a high-performance brain PET scanner operating in tandem with a total-body PET system for oncologic imaging applications. The project, designated R01CA308968, runs through July 31, 2031, with place of performance in Philadelphia, Pennsylvania. The University of Pennsylvania, in partnership with Siemens,...
The National Institute of Biomedical Imaging and Bioengineering awarded the University of California, Davis $615,615 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop next-generation whole-body positron emission tomography (PET) scanners with enhanced spatial resolution and timing performance. The research aims to achieve sub-2 millimeter spatial resolution and approximately 8 cubic millimeter volumetric resolution across the entire field of view, representing approximately two-fold and greater than six-fold improvement over state-of-the-art whole-body PET scanners, along with coincidence time resolution better than 150 picoseconds. These performance gains will enable clinical and research applications currently not feasible with existing scanners, including imaging of heterogeneous dose distributions, transmural cardiac defects, the spinal cord, vessel walls, and lymph nodes, as well as direct acquisition of image-derived input functions from the hepatic portal vein. The award funds research performed at the Davis, California campus with a period of performance extending from September 1, 2026, through May 31, 2030. The project grant assistance type supports hypothesis-driven research related to discovery, design, development, validation, and application of technologies for biomedical imaging and bioengineering as part of NIBIB's mission to advance understanding of disease prevention, detection, diagnosis, and treatment through technology development.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $615.6k | 8/18/26 |