This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health (CFDA 93.286) program, will support the development of an ultra-high spatial resolution photon-counting computed tomography (CT) system using multiple focal spots. The $536,954 award will fund research to create new data acquisition and reconstruction approaches that leverage both large and small X-ray focal spots to achieve high-resolution imaging with sufficient fluence to reduce noise. This innovative approach aims to overcome the limitations of current high-resolution CT systems, where smaller detector voxels require smaller X-ray focal spots that limit X-ray fluence and increase noise. Through a series of technical aims, the project will develop system models, evaluate focal spot strategies, and assess the performance of the multiple focal spot UHR-CT method on clinical photon-counting CT systems and animal models. Successful completion of this project could enable a new paradigm for ultra-high-resolution CT with potential for significant impact on a wide range of clinical diagnostic applications.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $537.0k | 3/20/25 |